Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cdkl5 | Pttg1ip | ENSMUSP00000084342 | ENSMUSP00000009435 | Cyclin-dependent kinase-like 5; Mediates phosphorylation of MECP2. May regulate ciliogenesis. | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | 0.422 |
| Pttg1 | Pttg1ip | ENSMUSP00000112815 | ENSMUSP00000009435 | Securin; Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however not limited to a blocking activity, since it is required to activate ESPL1. Negatively regulates the transcriptional activity a [...] | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | 0.854 |
| Pttg1 | Trp53 | ENSMUSP00000112815 | ENSMUSP00000104298 | Securin; Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however not limited to a blocking activity, since it is required to activate ESPL1. Negatively regulates the transcriptional activity a [...] | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.720 |
| Pttg1ip | Cdkl5 | ENSMUSP00000009435 | ENSMUSP00000084342 | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | Cyclin-dependent kinase-like 5; Mediates phosphorylation of MECP2. May regulate ciliogenesis. | 0.422 |
| Pttg1ip | Pttg1 | ENSMUSP00000009435 | ENSMUSP00000112815 | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | Securin; Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however not limited to a blocking activity, since it is required to activate ESPL1. Negatively regulates the transcriptional activity a [...] | 0.854 |
| Pttg1ip | Scpep1 | ENSMUSP00000009435 | ENSMUSP00000000287 | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | Retinoid-inducible serine carboxypeptidase; May be involved in vascular wall and kidney homeostasis; Belongs to the peptidase S10 family. | 0.605 |
| Pttg1ip | Snx22 | ENSMUSP00000009435 | ENSMUSP00000044389 | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | Sorting nexin 22. | 0.548 |
| Pttg1ip | Suox | ENSMUSP00000009435 | ENSMUSP00000056195 | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | Sulfite oxidase, mitochondrial. | 0.470 |
| Pttg1ip | Trp53 | ENSMUSP00000009435 | ENSMUSP00000104298 | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.553 |
| Scpep1 | Pttg1ip | ENSMUSP00000000287 | ENSMUSP00000009435 | Retinoid-inducible serine carboxypeptidase; May be involved in vascular wall and kidney homeostasis; Belongs to the peptidase S10 family. | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | 0.605 |
| Snx22 | Pttg1ip | ENSMUSP00000044389 | ENSMUSP00000009435 | Sorting nexin 22. | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | 0.548 |
| Suox | Pttg1ip | ENSMUSP00000056195 | ENSMUSP00000009435 | Sulfite oxidase, mitochondrial. | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | 0.470 |
| Trp53 | Pttg1 | ENSMUSP00000104298 | ENSMUSP00000112815 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Securin; Regulatory protein, which plays a central role in chromosome stability, in the p53/TP53 pathway, and DNA repair. Probably acts by blocking the action of key proteins. During the mitosis, it blocks Separase/ESPL1 function, preventing the proteolysis of the cohesin complex and the subsequent segregation of the chromosomes. At the onset of anaphase, it is ubiquitinated, conducting to its destruction and to the liberation of ESPL1. Its function is however not limited to a blocking activity, since it is required to activate ESPL1. Negatively regulates the transcriptional activity a [...] | 0.720 |
| Trp53 | Pttg1ip | ENSMUSP00000104298 | ENSMUSP00000009435 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | Pituitary tumor-transforming gene 1 protein-interacting protein; May facilitate PTTG1 nuclear translocation. | 0.553 |