node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adh1 | Gstm2 | ENSMUSP00000004232 | ENSMUSP00000012348 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Glutathione S-transferase Mu 2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | 0.797 |
Adh1 | Gstm5 | ENSMUSP00000004232 | ENSMUSP00000004134 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Glutathione S-transferase Mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | 0.698 |
Adh1 | Gsto1 | ENSMUSP00000004232 | ENSMUSP00000026050 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.682 |
Adh1 | Gstt1 | ENSMUSP00000004232 | ENSMUSP00000001713 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Glutathione S-transferase theta-1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity. | 0.742 |
Adh1 | Gstt2 | ENSMUSP00000004232 | ENSMUSP00000151239 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Glutathione S-transferase theta-2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.711 |
Adh1 | Gstt3 | ENSMUSP00000004232 | ENSMUSP00000001715 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Glutathione S-transferase theta-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Shows high activity towards 4-nitrobenzyl chloride (4-NBC). Also has lower activity towards 1,2-epoxy-3-(p-nitrophenoxy)propane (EPNP), cumene hydroperoxide, 1- chloro-2,4-dinitrobenzene (CDNB), 7-chloro-4-nitrobenzo-2-oxa-1,3- diazole (NBD-Cl), and ethacrynic acid. | 0.692 |
Cyp2c38 | Cyp2c39 | ENSMUSP00000044722 | ENSMUSP00000025968 | Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Cytochrome P450 2C39; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | 0.789 |
Cyp2c38 | Cyp2c55 | ENSMUSP00000044722 | ENSMUSP00000025966 | Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Cytochrome P450 2C55; Metabolizes arachidonic acid mainly to 19- hydroxyeicosatetraenoic acid (HETE); Belongs to the cytochrome P450 family. | 0.687 |
Cyp2c38 | Ephx1 | ENSMUSP00000044722 | ENSMUSP00000047551 | Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. | 0.917 |
Cyp2c38 | Gstm2 | ENSMUSP00000044722 | ENSMUSP00000012348 | Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Glutathione S-transferase Mu 2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | 0.832 |
Cyp2c38 | Gstm5 | ENSMUSP00000044722 | ENSMUSP00000004134 | Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Glutathione S-transferase Mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | 0.670 |
Cyp2c38 | Gsto1 | ENSMUSP00000044722 | ENSMUSP00000026050 | Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Glutathione S-transferase omega-1; Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid. Belongs to the GST superfamily. Omega family. | 0.671 |
Cyp2c38 | Gstt1 | ENSMUSP00000044722 | ENSMUSP00000001713 | Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Glutathione S-transferase theta-1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity. | 0.702 |
Cyp2c38 | Gstt2 | ENSMUSP00000044722 | ENSMUSP00000151239 | Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Glutathione S-transferase theta-2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.777 |
Cyp2c38 | Gstt3 | ENSMUSP00000044722 | ENSMUSP00000001715 | Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Glutathione S-transferase theta-3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Shows high activity towards 4-nitrobenzyl chloride (4-NBC). Also has lower activity towards 1,2-epoxy-3-(p-nitrophenoxy)propane (EPNP), cumene hydroperoxide, 1- chloro-2,4-dinitrobenzene (CDNB), 7-chloro-4-nitrobenzo-2-oxa-1,3- diazole (NBD-Cl), and ethacrynic acid. | 0.744 |
Cyp2c39 | Cyp2c38 | ENSMUSP00000025968 | ENSMUSP00000044722 | Cytochrome P450 2C39; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Cytochrome P450 2C38; Metabolizes arachidonic acid to produce 11,12- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | 0.789 |
Cyp2c39 | Cyp2c55 | ENSMUSP00000025968 | ENSMUSP00000025966 | Cytochrome P450 2C39; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Cytochrome P450 2C55; Metabolizes arachidonic acid mainly to 19- hydroxyeicosatetraenoic acid (HETE); Belongs to the cytochrome P450 family. | 0.686 |
Cyp2c39 | Ephx1 | ENSMUSP00000025968 | ENSMUSP00000047551 | Cytochrome P450 2C39; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Epoxide hydrolase 1; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. May play a role in the metabolism of endogenous lipids such as epoxide-containing fatty acids. Belongs to the peptidase S33 family. | 0.909 |
Cyp2c39 | Gstm2 | ENSMUSP00000025968 | ENSMUSP00000012348 | Cytochrome P450 2C39; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Glutathione S-transferase Mu 2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | 0.810 |
Cyp2c39 | Gstm5 | ENSMUSP00000025968 | ENSMUSP00000004134 | Cytochrome P450 2C39; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET); Belongs to the cytochrome P450 family. | Glutathione S-transferase Mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | 0.656 |