node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Chchd7 | Fam110b | ENSMUSP00000113811 | ENSMUSP00000062734 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 7; Belongs to the CHCHD7 family. | Protein FAM110B. | 0.514 |
Chchd7 | Lcorl | ENSMUSP00000113811 | ENSMUSP00000016026 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 7; Belongs to the CHCHD7 family. | Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis. | 0.618 |
Chchd7 | Ncapg | ENSMUSP00000113811 | ENSMUSP00000112871 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 7; Belongs to the CHCHD7 family. | Non-SMC condensin I complex, subunit G. | 0.558 |
Chchd7 | Plag1 | ENSMUSP00000113811 | ENSMUSP00000003369 | Coiled-coil-helix-coiled-coil-helix domain-containing protein 7; Belongs to the CHCHD7 family. | Zinc finger protein PLAG1; Transcription factor whose activation results in up- regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Cooperates with CBFB-MYH11. Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.780 |
Ctbp1 | Ctbp2 | ENSMUSP00000078682 | ENSMUSP00000130294 | C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. | C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Isoform 2 probably acts as a scaffold for specialized synapses (By similarity). Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.998 |
Ctbp1 | Lcorl | ENSMUSP00000078682 | ENSMUSP00000016026 | C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. | Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis. | 0.642 |
Ctbp2 | Ctbp1 | ENSMUSP00000130294 | ENSMUSP00000078682 | C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Isoform 2 probably acts as a scaffold for specialized synapses (By similarity). Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | C-terminal-binding protein 1; Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity. Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. | 0.998 |
Ctbp2 | Lcorl | ENSMUSP00000130294 | ENSMUSP00000016026 | C-terminal-binding protein 2; Corepressor targeting diverse transcription regulators. Isoform 2 probably acts as a scaffold for specialized synapses (By similarity). Functions in brown adipose tissue (BAT) differentiation. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis. | 0.549 |
Fam110b | Chchd7 | ENSMUSP00000062734 | ENSMUSP00000113811 | Protein FAM110B. | Coiled-coil-helix-coiled-coil-helix domain-containing protein 7; Belongs to the CHCHD7 family. | 0.514 |
Fam110b | Lcorl | ENSMUSP00000062734 | ENSMUSP00000016026 | Protein FAM110B. | Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis. | 0.528 |
Fam110b | Ncapg | ENSMUSP00000062734 | ENSMUSP00000112871 | Protein FAM110B. | Non-SMC condensin I complex, subunit G. | 0.535 |
Fam110b | Plag1 | ENSMUSP00000062734 | ENSMUSP00000003369 | Protein FAM110B. | Zinc finger protein PLAG1; Transcription factor whose activation results in up- regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Cooperates with CBFB-MYH11. Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.429 |
Fam184b | Lcorl | ENSMUSP00000016023 | ENSMUSP00000016026 | Protein FAM184B. | Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis. | 0.717 |
Fam184b | Ncapg | ENSMUSP00000016023 | ENSMUSP00000112871 | Protein FAM184B. | Non-SMC condensin I complex, subunit G. | 0.729 |
Hmga2 | Lcorl | ENSMUSP00000123998 | ENSMUSP00000016026 | High mobility group protein HMGI-C; Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation. | Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis. | 0.590 |
Hmga2 | Ncapg | ENSMUSP00000123998 | ENSMUSP00000112871 | High mobility group protein HMGI-C; Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation. | Non-SMC condensin I complex, subunit G. | 0.545 |
Hmga2 | Plag1 | ENSMUSP00000123998 | ENSMUSP00000003369 | High mobility group protein HMGI-C; Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation. | Zinc finger protein PLAG1; Transcription factor whose activation results in up- regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Cooperates with CBFB-MYH11. Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.544 |
Hmga2 | Zfat | ENSMUSP00000123998 | ENSMUSP00000125257 | High mobility group protein HMGI-C; Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation. | Zinc finger protein ZFAT; May be involved in transcriptional regulation. Overexpression causes down-regulation of a number of genes involved in the immune response. Some genes are also up-regulated. | 0.471 |
Lap3 | Lcorl | ENSMUSP00000040222 | ENSMUSP00000016026 | Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity). | Ligand-dependent nuclear receptor corepressor-like protein; May act as transcription activator that binds DNA elements with the sequence 5'-CCCTATCGATCGATCTCTACCT-3'. May play a role in spermatogenesis. | 0.632 |
Lap3 | Ncapg | ENSMUSP00000040222 | ENSMUSP00000112871 | Cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides (By similarity). | Non-SMC condensin I complex, subunit G. | 0.583 |