node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Actc1 | Myh3 | ENSMUSP00000087736 | ENSMUSP00000104329 | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Myosin-3; Muscle contraction. | 0.636 |
Actc1 | Myh6 | ENSMUSP00000087736 | ENSMUSP00000080538 | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Myosin-6; Muscle contraction. | 0.989 |
Actc1 | Myh7 | ENSMUSP00000087736 | ENSMUSP00000126840 | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.985 |
Actc1 | Myl2 | ENSMUSP00000087736 | ENSMUSP00000107380 | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function. Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites t [...] | 0.983 |
Actc1 | Myl3 | ENSMUSP00000087736 | ENSMUSP00000078715 | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.987 |
Actc1 | Myl4 | ENSMUSP00000087736 | ENSMUSP00000102570 | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Myosin light chain 4; Regulatory light chain of myosin. Does not bind calcium. | 0.969 |
Actc1 | Mylk2 | ENSMUSP00000087736 | ENSMUSP00000028970 | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Myosin light chain kinase 2, skeletal/cardiac muscle; Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain (By similarity). | 0.443 |
Actc1 | Tnni1 | ENSMUSP00000087736 | ENSMUSP00000123509 | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.607 |
Myh3 | Actc1 | ENSMUSP00000104329 | ENSMUSP00000087736 | Myosin-3; Muscle contraction. | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | 0.636 |
Myh3 | Myh6 | ENSMUSP00000104329 | ENSMUSP00000080538 | Myosin-3; Muscle contraction. | Myosin-6; Muscle contraction. | 0.695 |
Myh3 | Myh7 | ENSMUSP00000104329 | ENSMUSP00000126840 | Myosin-3; Muscle contraction. | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.742 |
Myh3 | Myl2 | ENSMUSP00000104329 | ENSMUSP00000107380 | Myosin-3; Muscle contraction. | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function. Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites t [...] | 0.851 |
Myh3 | Myl3 | ENSMUSP00000104329 | ENSMUSP00000078715 | Myosin-3; Muscle contraction. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.876 |
Myh3 | Myl4 | ENSMUSP00000104329 | ENSMUSP00000102570 | Myosin-3; Muscle contraction. | Myosin light chain 4; Regulatory light chain of myosin. Does not bind calcium. | 0.906 |
Myh3 | Tnni1 | ENSMUSP00000104329 | ENSMUSP00000123509 | Myosin-3; Muscle contraction. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.906 |
Myh6 | Actc1 | ENSMUSP00000080538 | ENSMUSP00000087736 | Myosin-6; Muscle contraction. | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. | 0.989 |
Myh6 | Myh3 | ENSMUSP00000080538 | ENSMUSP00000104329 | Myosin-6; Muscle contraction. | Myosin-3; Muscle contraction. | 0.695 |
Myh6 | Myh7 | ENSMUSP00000080538 | ENSMUSP00000126840 | Myosin-6; Muscle contraction. | Myosin-7; Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction. Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.933 |
Myh6 | Myl2 | ENSMUSP00000080538 | ENSMUSP00000107380 | Myosin-6; Muscle contraction. | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function. Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites t [...] | 0.992 |
Myh6 | Myl3 | ENSMUSP00000080538 | ENSMUSP00000078715 | Myosin-6; Muscle contraction. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.993 |