node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
4930444G20Rik | Lrp11 | ENSMUSP00000097613 | ENSMUSP00000019931 | RIKEN cDNA 4930444G20 gene. | Low-density lipoprotein receptor-related protein 11. | 0.499 |
Abitram | Lrp11 | ENSMUSP00000047275 | ENSMUSP00000019931 | Protein Abitram; Actin-binding protein that regulates actin polymerization, filopodia dynamics and increases the branching of proximal dendrites of developing neurons; Belongs to the ABITRAM family. | Low-density lipoprotein receptor-related protein 11. | 0.427 |
Abitram | Spryd7 | ENSMUSP00000047275 | ENSMUSP00000022497 | Protein Abitram; Actin-binding protein that regulates actin polymerization, filopodia dynamics and increases the branching of proximal dendrites of developing neurons; Belongs to the ABITRAM family. | SPRY domain-containing protein 7. | 0.607 |
Lrp10 | Lrp11 | ENSMUSP00000022782 | ENSMUSP00000019931 | Low-density lipoprotein receptor-related protein 10; Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver. | Low-density lipoprotein receptor-related protein 11. | 0.467 |
Lrp11 | 4930444G20Rik | ENSMUSP00000019931 | ENSMUSP00000097613 | Low-density lipoprotein receptor-related protein 11. | RIKEN cDNA 4930444G20 gene. | 0.499 |
Lrp11 | Abitram | ENSMUSP00000019931 | ENSMUSP00000047275 | Low-density lipoprotein receptor-related protein 11. | Protein Abitram; Actin-binding protein that regulates actin polymerization, filopodia dynamics and increases the branching of proximal dendrites of developing neurons; Belongs to the ABITRAM family. | 0.427 |
Lrp11 | Lrp10 | ENSMUSP00000019931 | ENSMUSP00000022782 | Low-density lipoprotein receptor-related protein 11. | Low-density lipoprotein receptor-related protein 10; Probable receptor, which is involved in the internalization of lipophilic molecules and/or signal transduction. May be involved in the uptake of lipoprotein APOE in liver. | 0.467 |
Lrp11 | Lrp12 | ENSMUSP00000019931 | ENSMUSP00000022916 | Low-density lipoprotein receptor-related protein 11. | Low-density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor (By similarity); Belongs to the LDLR family. | 0.569 |
Lrp11 | Lrp1b | ENSMUSP00000019931 | ENSMUSP00000054275 | Low-density lipoprotein receptor-related protein 11. | Low-density lipoprotein receptor-related protein 1B; Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis; Belongs to the LDLR family. | 0.510 |
Lrp11 | Lrp3 | ENSMUSP00000019931 | ENSMUSP00000114026 | Low-density lipoprotein receptor-related protein 11. | Low density lipoprotein receptor-related protein 3. | 0.612 |
Lrp11 | Lrp8 | ENSMUSP00000019931 | ENSMUSP00000102342 | Low-density lipoprotein receptor-related protein 11. | Low-density lipoprotein receptor-related protein 8; Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brai [...] | 0.474 |
Lrp11 | Olfr464 | ENSMUSP00000019931 | ENSMUSP00000149264 | Low-density lipoprotein receptor-related protein 11. | Olfactory receptor. | 0.511 |
Lrp11 | Sorl1 | ENSMUSP00000019931 | ENSMUSP00000058613 | Low-density lipoprotein receptor-related protein 11. | Sortilin-related receptor; Sorting receptor that directs several proteins to their correct location within the cell. Along with AP-1 complex, involved Golgi apparatus - endosome sorting. Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated. May also sort newly produced amyloid-beta peptides to lysosomes for catabolism. Does not affect APP trafficking from the endoplasmic r [...] | 0.498 |
Lrp11 | Spryd7 | ENSMUSP00000019931 | ENSMUSP00000022497 | Low-density lipoprotein receptor-related protein 11. | SPRY domain-containing protein 7. | 0.428 |
Lrp12 | Lrp11 | ENSMUSP00000022916 | ENSMUSP00000019931 | Low-density lipoprotein receptor-related protein 12; Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor (By similarity); Belongs to the LDLR family. | Low-density lipoprotein receptor-related protein 11. | 0.569 |
Lrp1b | Lrp11 | ENSMUSP00000054275 | ENSMUSP00000019931 | Low-density lipoprotein receptor-related protein 1B; Potential cell surface proteins that bind and internalize ligands in the process of receptor-mediated endocytosis; Belongs to the LDLR family. | Low-density lipoprotein receptor-related protein 11. | 0.510 |
Lrp3 | Lrp11 | ENSMUSP00000114026 | ENSMUSP00000019931 | Low density lipoprotein receptor-related protein 3. | Low-density lipoprotein receptor-related protein 11. | 0.612 |
Lrp8 | Lrp11 | ENSMUSP00000102342 | ENSMUSP00000019931 | Low-density lipoprotein receptor-related protein 8; Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brai [...] | Low-density lipoprotein receptor-related protein 11. | 0.474 |
Olfr464 | Lrp11 | ENSMUSP00000149264 | ENSMUSP00000019931 | Olfactory receptor. | Low-density lipoprotein receptor-related protein 11. | 0.511 |
Sorl1 | Lrp11 | ENSMUSP00000058613 | ENSMUSP00000019931 | Sortilin-related receptor; Sorting receptor that directs several proteins to their correct location within the cell. Along with AP-1 complex, involved Golgi apparatus - endosome sorting. Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated. May also sort newly produced amyloid-beta peptides to lysosomes for catabolism. Does not affect APP trafficking from the endoplasmic r [...] | Low-density lipoprotein receptor-related protein 11. | 0.498 |