Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ccdc59 | Llph | ENSMUSP00000020049 | ENSMUSP00000020444 | Thyroid transcription factor 1-associated protein 26; Component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC). Enhances homeobox protein Nkx-2.1-activated SFTPB and SFTPC promoter activities (By similarity); Belongs to the TAP26 family. | Protein LLP homolog; In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission. | 0.752 |
| Gnl2 | Gtpbp4 | ENSMUSP00000030684 | ENSMUSP00000152412 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.999 |
| Gnl2 | Llph | ENSMUSP00000030684 | ENSMUSP00000020444 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | Protein LLP homolog; In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission. | 0.616 |
| Gnl2 | Nhp2 | ENSMUSP00000030684 | ENSMUSP00000120014 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | H/ACA ribonucleoprotein complex subunit 2; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse tran [...] | 0.559 |
| Gnl2 | Nmd3 | ENSMUSP00000030684 | ENSMUSP00000029358 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. | 0.923 |
| Gnl2 | Rpl30 | ENSMUSP00000030684 | ENSMUSP00000106014 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. | 0.854 |
| Gnl2 | Rpl36al | ENSMUSP00000030684 | ENSMUSP00000106249 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | 60S ribosomal protein L36a. | 0.555 |
| Gnl2 | Zfp593 | ENSMUSP00000030684 | ENSMUSP00000030644 | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | Zinc finger protein 593; Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins (By similarity). | 0.988 |
| Gtpbp4 | Gnl2 | ENSMUSP00000152412 | ENSMUSP00000030684 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | 0.999 |
| Gtpbp4 | Llph | ENSMUSP00000152412 | ENSMUSP00000020444 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | Protein LLP homolog; In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission. | 0.626 |
| Gtpbp4 | Nhp2 | ENSMUSP00000152412 | ENSMUSP00000120014 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | H/ACA ribonucleoprotein complex subunit 2; Required for ribosome biogenesis and telomere maintenance. Part of the H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Each rRNA can contain up to 100 pseudouridine ('psi') residues, which may serve to stabilize the conformation of rRNAs. May also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse tran [...] | 0.695 |
| Gtpbp4 | Nmd3 | ENSMUSP00000152412 | ENSMUSP00000029358 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. | 0.994 |
| Gtpbp4 | Rpl30 | ENSMUSP00000152412 | ENSMUSP00000106014 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 60S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. | 0.929 |
| Gtpbp4 | Rpl36al | ENSMUSP00000152412 | ENSMUSP00000106249 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 60S ribosomal protein L36a. | 0.553 |
| Gtpbp4 | Zfp593 | ENSMUSP00000152412 | ENSMUSP00000030644 | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | Zinc finger protein 593; Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity. Could act either by binding to DNA octamer or by interacting with Oct-2. May also be a modulator of other octamer-binding proteins (By similarity). | 0.983 |
| Helb | Llph | ENSMUSP00000020449 | ENSMUSP00000020444 | DNA helicase B; 5'-3' DNA helicase involved in DNA damage response by acting as an inhibitor of DNA end resection. Recruitment to single-stranded DNA (ssDNA) following DNA damage leads to inhibit the nucleases catalyzing resection, such as EXO1, BLM and DNA2, possibly via the 5'-3' ssDNA translocase activity of HELB. As cells approach S phase, DNA end resection is promoted by the nuclear export of HELB following phosphorylation. Acts independently of TP53BP1. Unwinds duplex DNA with 5'- 3' polarity. Has single-strand DNA-dependent ATPase and DNA helicase activities. Prefers ATP and dAT [...] | Protein LLP homolog; In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission. | 0.655 |
| Llph | Ccdc59 | ENSMUSP00000020444 | ENSMUSP00000020049 | Protein LLP homolog; In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission. | Thyroid transcription factor 1-associated protein 26; Component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC). Enhances homeobox protein Nkx-2.1-activated SFTPB and SFTPC promoter activities (By similarity); Belongs to the TAP26 family. | 0.752 |
| Llph | Gnl2 | ENSMUSP00000020444 | ENSMUSP00000030684 | Protein LLP homolog; In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission. | Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation (By similarity). May promote cell proliferation possibly by increasing p53/TP53 protein levels, and consequently those of its downstream product CDKN1A/p21, and decreasing RPL23A protein levels (By similarity). | 0.616 |
| Llph | Gtpbp4 | ENSMUSP00000020444 | ENSMUSP00000152412 | Protein LLP homolog; In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission. | Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. | 0.626 |
| Llph | Helb | ENSMUSP00000020444 | ENSMUSP00000020449 | Protein LLP homolog; In hippocampal neurons, regulates dendritic and spine growth and synaptic transmission. | DNA helicase B; 5'-3' DNA helicase involved in DNA damage response by acting as an inhibitor of DNA end resection. Recruitment to single-stranded DNA (ssDNA) following DNA damage leads to inhibit the nucleases catalyzing resection, such as EXO1, BLM and DNA2, possibly via the 5'-3' ssDNA translocase activity of HELB. As cells approach S phase, DNA end resection is promoted by the nuclear export of HELB following phosphorylation. Acts independently of TP53BP1. Unwinds duplex DNA with 5'- 3' polarity. Has single-strand DNA-dependent ATPase and DNA helicase activities. Prefers ATP and dAT [...] | 0.655 |
page 1 of 4