STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Golga5Golgin subfamily A member 5; Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport (By similarity). (729 aa)    
Predicted Functional Partners:
Cog7
Conserved oligomeric Golgi complex subunit 7; Required for normal Golgi function.
   
  
 0.939
Trip11
Thyroid hormone receptor interactor 11.
   
  
 0.800
Gorasp1
Golgi reassembly-stacking protein 1; Plays an important role in assembly and membrane stacking of the Golgi cisternae, and in the reassembly of Golgi stacks after breakdown during mitosis. Key structural protein required for the maintenance of the Golgi apparatus integrity: its caspase-mediated cleavage is required for fragmentation of the Golgi during apoptosis (By similarity). Also mediates, via its interaction with GOLGA2/GM130, the docking of transport vesicles with the Golgi membranes (By similarity). Mediates ER stress-induced unconventional (ER/Golgi- independent) trafficking of [...]
   
  
 0.799
Golgb1
Golgi autoantigen, golgin subfamily b, macrogolgin 1.
   
  
 0.784
Cog3
Conserved oligomeric Golgi complex subunit 3; Involved in ER-Golgi transport.
   
  
 0.774
Blzf1
Golgin-45; Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface.
   
  
 0.771
Cog6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
  
 0.755
Gorasp2
Golgi reassembly-stacking protein 2; Plays a role in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after breakdown during mitosis and meiosis. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA (By similarity). Required for normal acrosome formation during spermiogenesis and normal male fertility, probably by promoting colocalization of JAM2 and JAM3 at contact sites between germ cells and Sertoli cells. Mediates ER stress-induced unconventional (ER/Gol [...]
   
  
 0.744
Cog8
Conserved oligomeric Golgi complex subunit 8; Required for normal Golgi function.
   
  
 0.731
Cog5
Conserved oligomeric Golgi complex subunit 5; Required for normal Golgi function.
   
  
 0.714
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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