node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adam2 | Adam22 | ENSMUSP00000022618 | ENSMUSP00000086139 | Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity). | Disintegrin and metalloproteinase domain-containing protein 22; Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation (By similarity). Neuronal receptor for LGI1. | 0.511 |
Adam2 | Adam28 | ENSMUSP00000022618 | ENSMUSP00000022642 | Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity). | Disintegrin and metalloproteinase domain-containing protein 28; May play a role in organogenesis and organ-specific functions such as thymic T-cell development. | 0.551 |
Adam2 | Adam7 | ENSMUSP00000022618 | ENSMUSP00000022640 | Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity). | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | 0.552 |
Adam22 | Adam2 | ENSMUSP00000086139 | ENSMUSP00000022618 | Disintegrin and metalloproteinase domain-containing protein 22; Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation (By similarity). Neuronal receptor for LGI1. | Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity). | 0.511 |
Adam22 | Adam28 | ENSMUSP00000086139 | ENSMUSP00000022642 | Disintegrin and metalloproteinase domain-containing protein 22; Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation (By similarity). Neuronal receptor for LGI1. | Disintegrin and metalloproteinase domain-containing protein 28; May play a role in organogenesis and organ-specific functions such as thymic T-cell development. | 0.707 |
Adam22 | Adam7 | ENSMUSP00000086139 | ENSMUSP00000022640 | Disintegrin and metalloproteinase domain-containing protein 22; Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation (By similarity). Neuronal receptor for LGI1. | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | 0.587 |
Adam28 | Adam2 | ENSMUSP00000022642 | ENSMUSP00000022618 | Disintegrin and metalloproteinase domain-containing protein 28; May play a role in organogenesis and organ-specific functions such as thymic T-cell development. | Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity). | 0.551 |
Adam28 | Adam22 | ENSMUSP00000022642 | ENSMUSP00000086139 | Disintegrin and metalloproteinase domain-containing protein 28; May play a role in organogenesis and organ-specific functions such as thymic T-cell development. | Disintegrin and metalloproteinase domain-containing protein 22; Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation (By similarity). Neuronal receptor for LGI1. | 0.707 |
Adam28 | Adam7 | ENSMUSP00000022642 | ENSMUSP00000022640 | Disintegrin and metalloproteinase domain-containing protein 28; May play a role in organogenesis and organ-specific functions such as thymic T-cell development. | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | 0.566 |
Adam28 | Cst11 | ENSMUSP00000022642 | ENSMUSP00000028934 | Disintegrin and metalloproteinase domain-containing protein 28; May play a role in organogenesis and organ-specific functions such as thymic T-cell development. | Cystatin-11; Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization. Belongs to the cystatin family. | 0.432 |
Adam7 | Adam2 | ENSMUSP00000022640 | ENSMUSP00000022618 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Disintegrin and metalloproteinase domain-containing protein 2; Sperm surface membrane protein that may be involved in sperm- egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity). | 0.552 |
Adam7 | Adam22 | ENSMUSP00000022640 | ENSMUSP00000086139 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Disintegrin and metalloproteinase domain-containing protein 22; Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation (By similarity). Neuronal receptor for LGI1. | 0.587 |
Adam7 | Adam28 | ENSMUSP00000022640 | ENSMUSP00000022642 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Disintegrin and metalloproteinase domain-containing protein 28; May play a role in organogenesis and organ-specific functions such as thymic T-cell development. | 0.566 |
Adam7 | Ces5a | ENSMUSP00000022640 | ENSMUSP00000148481 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Carboxylesterase 5A; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | 0.581 |
Adam7 | Cst11 | ENSMUSP00000022640 | ENSMUSP00000028934 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Cystatin-11; Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization. Belongs to the cystatin family. | 0.597 |
Adam7 | Gpx5 | ENSMUSP00000022640 | ENSMUSP00000106117 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids. | 0.717 |
Adam7 | Lcn5 | ENSMUSP00000022640 | ENSMUSP00000028306 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Epididymal-specific lipocalin-5, major form; Associates with spermatozoa in the epididymal fluid but does not bind tightly to them. Binds both all-trans and 13-cis retinoic acid. May act as a retinoid carrier protein which is required for epididymal function and/or sperm maturation. Belongs to the calycin superfamily. Lipocalin family. | 0.679 |
Adam7 | Lcn8 | ENSMUSP00000022640 | ENSMUSP00000043902 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis. | 0.744 |
Adam7 | Lcn9 | ENSMUSP00000022640 | ENSMUSP00000023978 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Epididymal-specific lipocalin-9. | 0.771 |
Adam7 | Zfp511 | ENSMUSP00000022640 | ENSMUSP00000129154 | Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein. | Zinc finger protein 511; May be involved in transcriptional regulation. | 0.623 |