• Version:
  • 11.0 (preview - - version 10.5 still available here)
STRINGSTRING
Adam7 protein (mouse) - STRING interaction network
"Adam7" - Disintegrin and metalloproteinase domain-containing protein 7 in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adam7Disintegrin and metalloproteinase domain-containing protein 7; May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein (789 aa)    
Predicted Functional Partners:
Lcn8
Epididymal-specific lipocalin-8; May play a role in male fertility. May act as a retinoid carrier protein within the epididymis (175 aa)
     
   
  0.847
Cst11
Cystatin-11; Cystatin 11 (139 aa)
     
   
  0.828
Crisp1
Cysteine-rich secretory protein 1; This protein is supposed to help spermatozoa undergo functional maturation while they move from the testis to the ductus deferens (244 aa)
     
   
  0.816
Gpx5
Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids (237 aa)
     
   
  0.773
Cst12
Cystatin-12; May play a specialized role in spermatogenesis (141 aa)
     
   
  0.741
Crisp3
Cysteine-rich secretory protein 3; This protein is supposed to help spermatozoa undergo functional maturation while they move from the testis to the ductus deferens; Belongs to the CRISP family (241 aa)
     
        0.701
mCG_7467
RIKEN cDNA D730048I06 gene (106 aa)
     
        0.688
mCG_18947
Cystatin; RIKEN cDNA 9230104L09 gene; Belongs to the cystatin family (133 aa)
     
   
  0.674
Ces5a
Carboxylesterase 5A; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family (575 aa)
     
        0.658
Lcn9
Epididymal-specific lipocalin-9; Lipocalin 9 (178 aa)
     
   
  0.657
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
Server load: low (9%) [HD]