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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fam135bProtein FAM135B; Belongs to the FAM135 family. (1403 aa)    
Predicted Functional Partners:
Adam29
Disintegrin and metalloproteinase domain-containing protein 29; May be involved in spermatogenesis and fertilization. Seems to be a non catalytic metalloprotease-like protein (By similarity).
   
  
 0.675
Golga7b
Golgin subfamily A member 7B; May be involved in protein transport from Golgi to cell surface; Belongs to the ERF4 family.
   
  
 0.538
Fam177a2
Family with sequence similarity 177 member A2.
      
 0.498
Csmd3
CUB and sushi domain-containing protein 3; Involved in dendrite development.
   
  
 0.465
Zfp750
Zinc finger protein 750; Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression (By similarity).
      
 0.461
Fat2
Protocadherin Fat 2; Involved in the regulation of cell migration (By similarity). May be involved in mediating the organization of the parallel fibers of granule cells during cerebellar development (By similarity).
   
  
 0.452
Fam177a
Protein FAM177A1; Belongs to the FAM177 family.
      
 0.429
Fam110a
Protein FAM110A; Belongs to the FAM110 family.
      
 0.428
Fat1
FAT atypical cadherin 1.
      
 0.426
Fam43b
Family with sequence similarity 43, member B.
   
  
 0.407
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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