node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccdc103 | Ccdc39 | ENSMUSP00000021307 | ENSMUSP00000029222 | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | 0.808 |
Ccdc103 | Dnaaf3 | ENSMUSP00000021307 | ENSMUSP00000092498 | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | Dynein assembly factor 3, axonemal; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia (By similarity); Belongs to the DNAAF3 family. | 0.812 |
Ccdc103 | Dnaaf4 | ENSMUSP00000021307 | ENSMUSP00000034734 | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity (By similarity). Axonemal dynein assembly factor required for ciliary motility. | 0.756 |
Ccdc103 | Dnaaf5 | ENSMUSP00000021307 | ENSMUSP00000026975 | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility. | 0.791 |
Ccdc103 | Dnaic1 | ENSMUSP00000021307 | ENSMUSP00000100028 | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | Dynein intermediate chain 1, axonemal; Part of the dynein complex of respiratory cilia. | 0.859 |
Ccdc103 | Dnaic2 | ENSMUSP00000021307 | ENSMUSP00000065787 | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | Dynein intermediate chain 2, axonemal; Part of the dynein complex of respiratory cilia. | 0.888 |
Ccdc103 | Lrrc6 | ENSMUSP00000021307 | ENSMUSP00000023006 | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | Protein tilB homolog; May play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility; Belongs to the tilB family. | 0.833 |
Ccdc103 | Pih1d3 | ENSMUSP00000021307 | ENSMUSP00000127665 | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | Protein PIH1D3; Plays a role in cytoplasmic pre-assembly of axonemal dynein. | 0.656 |
Ccdc103 | Spag1 | ENSMUSP00000021307 | ENSMUSP00000047335 | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | Sperm-associated antigen 1; May play a role in the cytoplasmic assembly of the ciliary dynein arms (By similarity). May play a role in fertilization. Binds GTP and has GTPase activity (By similarity). | 0.783 |
Ccdc103 | Zmynd10 | ENSMUSP00000021307 | ENSMUSP00000010188 | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins (By similarity); Belongs to the ZMYND10 family. | 0.803 |
Ccdc39 | Ccdc103 | ENSMUSP00000029222 | ENSMUSP00000021307 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Coiled-coil domain-containing protein 103; Dynein-attachment factor required for cilia motility. | 0.808 |
Ccdc39 | Dnaaf3 | ENSMUSP00000029222 | ENSMUSP00000092498 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Dynein assembly factor 3, axonemal; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia (By similarity); Belongs to the DNAAF3 family. | 0.812 |
Ccdc39 | Dnaaf4 | ENSMUSP00000029222 | ENSMUSP00000034734 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Dynein assembly factor 4, axonemal; Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity (By similarity). Axonemal dynein assembly factor required for ciliary motility. | 0.687 |
Ccdc39 | Dnaaf5 | ENSMUSP00000029222 | ENSMUSP00000026975 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Dynein assembly factor 5, axonemal; Cytoplasmic protein involved in the delivery of the dynein machinery to the motile cilium. It is required for the assembly of the axonemal dynein inner and outer arms, two structures attached to the peripheral outer doublet A microtubule of the axoneme, that play a crucial role in cilium motility. | 0.723 |
Ccdc39 | Dnaic1 | ENSMUSP00000029222 | ENSMUSP00000100028 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Dynein intermediate chain 1, axonemal; Part of the dynein complex of respiratory cilia. | 0.788 |
Ccdc39 | Dnaic2 | ENSMUSP00000029222 | ENSMUSP00000065787 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Dynein intermediate chain 2, axonemal; Part of the dynein complex of respiratory cilia. | 0.827 |
Ccdc39 | Lrrc6 | ENSMUSP00000029222 | ENSMUSP00000023006 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Protein tilB homolog; May play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility; Belongs to the tilB family. | 0.807 |
Ccdc39 | Pih1d3 | ENSMUSP00000029222 | ENSMUSP00000127665 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Protein PIH1D3; Plays a role in cytoplasmic pre-assembly of axonemal dynein. | 0.565 |
Ccdc39 | Spag1 | ENSMUSP00000029222 | ENSMUSP00000047335 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Sperm-associated antigen 1; May play a role in the cytoplasmic assembly of the ciliary dynein arms (By similarity). May play a role in fertilization. Binds GTP and has GTPase activity (By similarity). | 0.697 |
Ccdc39 | Zmynd10 | ENSMUSP00000029222 | ENSMUSP00000010188 | Coiled-coil domain-containing protein 39; Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella. Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella. Not required for outer dynein arm complexes assembly. | Zinc finger MYND domain-containing protein 10; Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins (By similarity); Belongs to the ZMYND10 family. | 0.790 |