node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atp1b2 | Krt2 | ENSMUSP00000047353 | ENSMUSP00000023712 | Sodium/potassium-transporting ATPase subunit beta-2; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is not known. | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin. | 0.576 |
Flg | Krt1 | ENSMUSP00000142003 | ENSMUSP00000023790 | Filaggrin. | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. | 0.921 |
Flg | Krt10 | ENSMUSP00000142003 | ENSMUSP00000099420 | Filaggrin. | Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Belongs to the intermediate filament family. | 0.935 |
Flg | Krt2 | ENSMUSP00000142003 | ENSMUSP00000023712 | Filaggrin. | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin. | 0.630 |
Flg | Krt5 | ENSMUSP00000142003 | ENSMUSP00000023709 | Filaggrin. | Keratin, type II cytoskeletal 5. | 0.717 |
Flg | Krtdap | ENSMUSP00000142003 | ENSMUSP00000096159 | Filaggrin. | Keratinocyte differentiation-associated protein; May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis (By similarity). | 0.523 |
Flg | Lor | ENSMUSP00000142003 | ENSMUSP00000052128 | Filaggrin. | Loricrin; Major keratinocyte cell envelope protein. | 0.996 |
Krt1 | Flg | ENSMUSP00000023790 | ENSMUSP00000142003 | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. | Filaggrin. | 0.921 |
Krt1 | Krt10 | ENSMUSP00000023790 | ENSMUSP00000099420 | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. | Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Belongs to the intermediate filament family. | 0.972 |
Krt1 | Krt2 | ENSMUSP00000023790 | ENSMUSP00000023712 | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin. | 0.698 |
Krt1 | Krt5 | ENSMUSP00000023790 | ENSMUSP00000023709 | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 5. | 0.661 |
Krt1 | Krt77 | ENSMUSP00000023790 | ENSMUSP00000085311 | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 1b. | 0.769 |
Krt1 | Krt79 | ENSMUSP00000023790 | ENSMUSP00000023799 | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 79; Belongs to the intermediate filament family. | 0.564 |
Krt1 | Krtdap | ENSMUSP00000023790 | ENSMUSP00000096159 | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. | Keratinocyte differentiation-associated protein; May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis (By similarity). | 0.671 |
Krt1 | Lor | ENSMUSP00000023790 | ENSMUSP00000052128 | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. | Loricrin; Major keratinocyte cell envelope protein. | 0.904 |
Krt10 | Flg | ENSMUSP00000099420 | ENSMUSP00000142003 | Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Belongs to the intermediate filament family. | Filaggrin. | 0.935 |
Krt10 | Krt1 | ENSMUSP00000099420 | ENSMUSP00000023790 | Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 1; May regulate the activity of kinases such as PKC and SRC via binding to integrin beta-1 (ITB1) and the receptor of activated protein C kinase 1 (RACK1). In complex with C1QBP is a high affinity receptor for kininogen-1/HMWK (By similarity); Belongs to the intermediate filament family. | 0.972 |
Krt10 | Krt2 | ENSMUSP00000099420 | ENSMUSP00000023712 | Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin. | 0.653 |
Krt10 | Krt5 | ENSMUSP00000099420 | ENSMUSP00000023709 | Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 5. | 0.573 |
Krt10 | Krt79 | ENSMUSP00000099420 | ENSMUSP00000023799 | Keratin, type I cytoskeletal 10; Plays a role in the establishment of the epidermal barrier on plantar skin. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 79; Belongs to the intermediate filament family. | 0.701 |