| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| B4galt1 | B4galt2 | ENSMUSP00000030121 | ENSMUSP00000030266 | Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | Beta-1,4-galactosyltransferase 2; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose (By similarity). | 0.938 |
| B4galt1 | Gale | ENSMUSP00000030121 | ENSMUSP00000099599 | Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...] | 0.922 |
| B4galt1 | Glb1 | ENSMUSP00000030121 | ENSMUSP00000055803 | Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | 0.909 |
| B4galt1 | Lalba | ENSMUSP00000030121 | ENSMUSP00000023726 | Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins. | 0.998 |
| B4galt1 | Lct | ENSMUSP00000030121 | ENSMUSP00000073190 | Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | Lactase. | 0.877 |
| B4galt2 | B4galt1 | ENSMUSP00000030266 | ENSMUSP00000030121 | Beta-1,4-galactosyltransferase 2; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose (By similarity). | Processed beta-1,4-galactosyltransferase 1; The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | 0.938 |
| B4galt2 | Gale | ENSMUSP00000030266 | ENSMUSP00000099599 | Beta-1,4-galactosyltransferase 2; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose (By similarity). | UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...] | 0.891 |
| B4galt2 | Glb1 | ENSMUSP00000030266 | ENSMUSP00000055803 | Beta-1,4-galactosyltransferase 2; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose (By similarity). | Beta-galactosidase; Cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. Belongs to the glycosyl hydrolase 35 family. | 0.886 |
| B4galt2 | Lalba | ENSMUSP00000030266 | ENSMUSP00000023726 | Beta-1,4-galactosyltransferase 2; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose (By similarity). | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins. | 0.955 |
| B4galt2 | Lct | ENSMUSP00000030266 | ENSMUSP00000073190 | Beta-1,4-galactosyltransferase 2; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose (By similarity). | Lactase. | 0.877 |
| Csn1s1 | Csn2 | ENSMUSP00000092225 | ENSMUSP00000143341 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Beta-casein; Important role in determination of the surface properties of the casein micelles. | 0.997 |
| Csn1s1 | Csn3 | ENSMUSP00000092225 | ENSMUSP00000108896 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. | 0.988 |
| Csn1s1 | Glycam1 | ENSMUSP00000092225 | ENSMUSP00000023134 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Glycosylation-dependent cell adhesion molecule 1; Adhesion molecule that accomplishes cell binding by presenting carbohydrate(s) to the lectin domain of L-selectin; Belongs to the PP3/GlyCAM-1 family. | 0.747 |
| Csn1s1 | Lalba | ENSMUSP00000092225 | ENSMUSP00000023726 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins. | 0.977 |
| Csn1s1 | Ltf | ENSMUSP00000092225 | ENSMUSP00000035077 | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. | 0.611 |
| Csn2 | Csn1s1 | ENSMUSP00000143341 | ENSMUSP00000092225 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate. | 0.997 |
| Csn2 | Csn3 | ENSMUSP00000143341 | ENSMUSP00000108896 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk. | 0.991 |
| Csn2 | Glycam1 | ENSMUSP00000143341 | ENSMUSP00000023134 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Glycosylation-dependent cell adhesion molecule 1; Adhesion molecule that accomplishes cell binding by presenting carbohydrate(s) to the lectin domain of L-selectin; Belongs to the PP3/GlyCAM-1 family. | 0.877 |
| Csn2 | Lalba | ENSMUSP00000143341 | ENSMUSP00000023726 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins. | 0.979 |
| Csn2 | Ltf | ENSMUSP00000143341 | ENSMUSP00000035077 | Beta-casein; Important role in determination of the surface properties of the casein micelles. | Lactotransferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity. Shows a preferential cleavage at -Arg-Ser-Arg-Arg-|- and -Arg-Arg-Ser-Arg-|-, and of Z-Phe-Arg-|-aminomethylcoumarin sites. | 0.659 |
