node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
4930595M18Rik | Mospd1 | ENSMUSP00000078984 | ENSMUSP00000023836 | RIKEN cDNA 4930595M18 gene. | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | 0.519 |
4930595M18Rik | Rhox4g | ENSMUSP00000078984 | ENSMUSP00000110820 | RIKEN cDNA 4930595M18 gene. | Reproductive homeobox 4G. | 0.664 |
Antxrl | Mospd1 | ENSMUSP00000052816 | ENSMUSP00000023836 | Anthrax toxin receptor-like. | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | 0.559 |
Cep85 | Mospd1 | ENSMUSP00000039889 | ENSMUSP00000023836 | Centrosomal protein of 85 kDa; Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase. Suppresses centrosome disjunction by inhibiting NEK2 kinase activity; Belongs to the CEP85 family. | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | 0.514 |
Cfap65 | Mospd1 | ENSMUSP00000092440 | ENSMUSP00000023836 | Cilia- and flagella-associated protein 65; May play a role in sperm motility. Belongs to the CFAP65 family. | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | 0.534 |
Mospd1 | 4930595M18Rik | ENSMUSP00000023836 | ENSMUSP00000078984 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | RIKEN cDNA 4930595M18 gene. | 0.519 |
Mospd1 | Antxrl | ENSMUSP00000023836 | ENSMUSP00000052816 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | Anthrax toxin receptor-like. | 0.559 |
Mospd1 | Cep85 | ENSMUSP00000023836 | ENSMUSP00000039889 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | Centrosomal protein of 85 kDa; Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase. Suppresses centrosome disjunction by inhibiting NEK2 kinase activity; Belongs to the CEP85 family. | 0.514 |
Mospd1 | Cfap65 | ENSMUSP00000023836 | ENSMUSP00000092440 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | Cilia- and flagella-associated protein 65; May play a role in sperm motility. Belongs to the CFAP65 family. | 0.534 |
Mospd1 | Mospd2 | ENSMUSP00000023836 | ENSMUSP00000004715 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | Motile sperm domain-containing protein 2; Promotes migration of primary monocytes and neutrophils, in response to various chemokines. | 0.741 |
Mospd1 | Nkx3-2 | ENSMUSP00000023836 | ENSMUSP00000051990 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | Homeobox protein Nkx-3.2; Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus. Belongs to the NK-3 homeobox family. | 0.520 |
Mospd1 | Osbp | ENSMUSP00000023836 | ENSMUSP00000025590 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | Oxysterol-binding protein 1; Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds cholesterol and a range of oxysterols including 25- hydroxycholesterol. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol [...] | 0.563 |
Mospd1 | Rhox4g | ENSMUSP00000023836 | ENSMUSP00000110820 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | Reproductive homeobox 4G. | 0.538 |
Mospd1 | Stard3nl | ENSMUSP00000023836 | ENSMUSP00000142680 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | STARD3 N-terminal-like protein; Tethering protein that creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum via interaction with VAPA and VAPB. | 0.537 |
Mospd1 | Vapa | ENSMUSP00000023836 | ENSMUSP00000024897 | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | Vesicle-associated membrane protein-associated protein A; Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With OSBPL3, may regulate ER morphology. May play a role in vesicle trafficking; Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. | 0.526 |
Mospd2 | Mospd1 | ENSMUSP00000004715 | ENSMUSP00000023836 | Motile sperm domain-containing protein 2; Promotes migration of primary monocytes and neutrophils, in response to various chemokines. | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | 0.741 |
Mospd2 | Osbp | ENSMUSP00000004715 | ENSMUSP00000025590 | Motile sperm domain-containing protein 2; Promotes migration of primary monocytes and neutrophils, in response to various chemokines. | Oxysterol-binding protein 1; Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum: specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1/SACM1L phosphatase in the endoplasmic reticulum. Binds cholesterol and a range of oxysterols including 25- hydroxycholesterol. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylates ERK1/2, whereas 25-hydroxycholesterol [...] | 0.603 |
Mospd2 | Stard3nl | ENSMUSP00000004715 | ENSMUSP00000142680 | Motile sperm domain-containing protein 2; Promotes migration of primary monocytes and neutrophils, in response to various chemokines. | STARD3 N-terminal-like protein; Tethering protein that creates contact site between the endoplasmic reticulum and late endosomes: localizes to late endosome membranes and contacts the endoplasmic reticulum via interaction with VAPA and VAPB. | 0.664 |
Mospd2 | Vapa | ENSMUSP00000004715 | ENSMUSP00000024897 | Motile sperm domain-containing protein 2; Promotes migration of primary monocytes and neutrophils, in response to various chemokines. | Vesicle-associated membrane protein-associated protein A; Binds to OSBPL3, which mediates recruitment of VAPA to plasma membrane sites. The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface. With OSBPL3, may regulate ER morphology. May play a role in vesicle trafficking; Belongs to the VAMP-associated protein (VAP) (TC 9.B.17) family. | 0.490 |
Nkx3-2 | Mospd1 | ENSMUSP00000051990 | ENSMUSP00000023836 | Homeobox protein Nkx-3.2; Transcriptional repressor that acts as a negative regulator of chondrocyte maturation. PLays a role in distal stomach development; required for proper antral-pyloric morphogenesis and development of antral-type epithelium. In concert with GSC, defines the structural components of the middle ear; required for tympanic ring and gonium development and in the regulation of the width of the malleus. Belongs to the NK-3 homeobox family. | Motile sperm domain-containing protein 1; Plays a role in differentiation and/or proliferation of mesenchymal stem cells. Proposed to be involved in epithelial-to-mesenchymal transition (EMT). However, another study suggests that it is not required for EMT or stem cell self-renewal and acts during later stages of differentiation. | 0.520 |