node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Chst14 | Paqr4 | ENSMUSP00000099579 | ENSMUSP00000024702 | Carbohydrate sulfotransferase 14; Catalyzes the transfer of sulfate to position 4 of the N- acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may [...] | Progestin and adipoQ receptor family member 4. | 0.486 |
Creb3l4 | Paqr4 | ENSMUSP00000029547 | ENSMUSP00000024702 | Processed cyclic AMP-responsive element-binding protein 3-like protein 4; Transcriptional activator that may play a role in the unfolded protein response of the testis. Proposed to be involved in spermiogenesis. May be involved in regulating the maturation of sperm head nuclei. Alternatively proposed to be a paternally delivered transcription factor that may function in early zygotic gene activation. Increases the binding of CREM isoform Tau with CRE. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE but not through UPRE and may recruit HIRA to CRE to regulate histone exchange. | Progestin and adipoQ receptor family member 4. | 0.580 |
Flywch1 | Paqr4 | ENSMUSP00000040022 | ENSMUSP00000024702 | FLYWCH-type zinc finger-containing protein 1. | Progestin and adipoQ receptor family member 4. | 0.587 |
Flywch1 | Prss41 | ENSMUSP00000040022 | ENSMUSP00000024926 | FLYWCH-type zinc finger-containing protein 1. | Serine protease 41; Belongs to the peptidase S1 family. | 0.532 |
Mmd | Paqr4 | ENSMUSP00000004050 | ENSMUSP00000024702 | Monocyte to macrophage differentiation factor; Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion; Belongs to the ADIPOR family. | Progestin and adipoQ receptor family member 4. | 0.645 |
Mmd2 | Paqr4 | ENSMUSP00000039357 | ENSMUSP00000024702 | Monocyte to macrophage differentiation factor 2; Belongs to the ADIPOR family. | Progestin and adipoQ receptor family member 4. | 0.425 |
Myadml2 | Paqr4 | ENSMUSP00000026134 | ENSMUSP00000024702 | Myeloid-associated differentiation marker-like protein 2; Belongs to the MAL family. | Progestin and adipoQ receptor family member 4. | 0.443 |
Paqr4 | Chst14 | ENSMUSP00000024702 | ENSMUSP00000099579 | Progestin and adipoQ receptor family member 4. | Carbohydrate sulfotransferase 14; Catalyzes the transfer of sulfate to position 4 of the N- acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-0-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may [...] | 0.486 |
Paqr4 | Creb3l4 | ENSMUSP00000024702 | ENSMUSP00000029547 | Progestin and adipoQ receptor family member 4. | Processed cyclic AMP-responsive element-binding protein 3-like protein 4; Transcriptional activator that may play a role in the unfolded protein response of the testis. Proposed to be involved in spermiogenesis. May be involved in regulating the maturation of sperm head nuclei. Alternatively proposed to be a paternally delivered transcription factor that may function in early zygotic gene activation. Increases the binding of CREM isoform Tau with CRE. The CREM isoform Tau-CREB3L4 heterodimer functions through CRE but not through UPRE and may recruit HIRA to CRE to regulate histone exchange. | 0.580 |
Paqr4 | Flywch1 | ENSMUSP00000024702 | ENSMUSP00000040022 | Progestin and adipoQ receptor family member 4. | FLYWCH-type zinc finger-containing protein 1. | 0.587 |
Paqr4 | Mmd | ENSMUSP00000024702 | ENSMUSP00000004050 | Progestin and adipoQ receptor family member 4. | Monocyte to macrophage differentiation factor; Involved in the dynamics of lysosomal membranes associated with microglial activation following brain lesion; Belongs to the ADIPOR family. | 0.645 |
Paqr4 | Mmd2 | ENSMUSP00000024702 | ENSMUSP00000039357 | Progestin and adipoQ receptor family member 4. | Monocyte to macrophage differentiation factor 2; Belongs to the ADIPOR family. | 0.425 |
Paqr4 | Myadml2 | ENSMUSP00000024702 | ENSMUSP00000026134 | Progestin and adipoQ receptor family member 4. | Myeloid-associated differentiation marker-like protein 2; Belongs to the MAL family. | 0.443 |
Paqr4 | Paqr9 | ENSMUSP00000024702 | ENSMUSP00000078547 | Progestin and adipoQ receptor family member 4. | Membrane progesterone receptor epsilon; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(s) mediated pathway. May be involved in regulating rapid P4 signaling in the nervous system. Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone; Belongs to the ADIPOR family. | 0.424 |
Paqr4 | Pkmyt1 | ENSMUSP00000024702 | ENSMUSP00000024701 | Progestin and adipoQ receptor family member 4. | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development (By similarity); Belongs to the protein ki [...] | 0.472 |
Paqr4 | Prss41 | ENSMUSP00000024702 | ENSMUSP00000024926 | Progestin and adipoQ receptor family member 4. | Serine protease 41; Belongs to the peptidase S1 family. | 0.439 |
Paqr4 | Tpd52 | ENSMUSP00000024702 | ENSMUSP00000091943 | Progestin and adipoQ receptor family member 4. | Tumor protein D52; Belongs to the TPD52 family. | 0.626 |
Paqr9 | Paqr4 | ENSMUSP00000078547 | ENSMUSP00000024702 | Membrane progesterone receptor epsilon; Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(s) mediated pathway. May be involved in regulating rapid P4 signaling in the nervous system. Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone; Belongs to the ADIPOR family. | Progestin and adipoQ receptor family member 4. | 0.424 |
Pkmyt1 | Paqr4 | ENSMUSP00000024701 | ENSMUSP00000024702 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development (By similarity); Belongs to the protein ki [...] | Progestin and adipoQ receptor family member 4. | 0.472 |
Pkmyt1 | Prss41 | ENSMUSP00000024701 | ENSMUSP00000024926 | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase; Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development (By similarity); Belongs to the protein ki [...] | Serine protease 41; Belongs to the peptidase S1 family. | 0.428 |