STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sult1c1Sulfotransferase 1C1; Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hydroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). Also shows activity towards cinnamyl alcohol at pH 6.4 but not at pH 5.5, and towards a number of phenolic odorants including eugenol, guaiacol and 2-naphthol. (304 aa)    
Predicted Functional Partners:
Chst10
Carbohydrate sulfotransferase 10; Catalyzes the transfer of sulfate to position 3 of terminal glucuronic acid of both protein- and lipid-linked oligosaccharides. Participates in biosynthesis of HNK-1 carbohydrate structure, a sulfated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult. May be indirectly involved in synapse plasticity of the hippocampus, via its role in HNK-1 biosynthesis; Belongs to the sulfotransferase 2 family.
      
 0.538
Slc35a2
UDP-galactose translocator; Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function.
      
 0.524
Ugt1a10
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.516
Ugt2b1
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.514
Ugt1a1
UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
   
  
 0.513
Ugt1a6b
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.509
Ugt2b34
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.497
Ugt2b36
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.491
Ugt2b35
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.489
Ugt1a5
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.488
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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