node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aspdh | Jpt2 | ENSMUSP00000039202 | ENSMUSP00000024981 | Putative L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. | Jupiter microtubule associated homolog 2. | 0.508 |
Cramp1l | Jpt2 | ENSMUSP00000156906 | ENSMUSP00000024981 | Protein cramped-like. | Jupiter microtubule associated homolog 2. | 0.558 |
Cramp1l | Mtrex | ENSMUSP00000156906 | ENSMUSP00000022281 | Protein cramped-like. | Exosome RNA helicase MTR4; Catalyzes the ATP-dependent unwinding of RNA duplexes with a single-stranded 3' RNA extension. Central subunit of many protein complexes, namely TRAMP-like, nuclear exosome targeting (NEXT) and poly(A) tail exosome targeting (PAXT). NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. PAXT directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental f [...] | 0.562 |
Jpt1 | Jpt2 | ENSMUSP00000021083 | ENSMUSP00000024981 | Jupiter microtubule associated homolog 1, N-terminally processed; Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (By similarity). Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (By similarity). | Jupiter microtubule associated homolog 2. | 0.615 |
Jpt2 | Aspdh | ENSMUSP00000024981 | ENSMUSP00000039202 | Jupiter microtubule associated homolog 2. | Putative L-aspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. | 0.508 |
Jpt2 | Cramp1l | ENSMUSP00000024981 | ENSMUSP00000156906 | Jupiter microtubule associated homolog 2. | Protein cramped-like. | 0.558 |
Jpt2 | Jpt1 | ENSMUSP00000024981 | ENSMUSP00000021083 | Jupiter microtubule associated homolog 2. | Jupiter microtubule associated homolog 1, N-terminally processed; Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (By similarity). Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (By similarity). | 0.615 |
Jpt2 | Lsm12 | ENSMUSP00000024981 | ENSMUSP00000021297 | Jupiter microtubule associated homolog 2. | Protein LSM12 homolog; Belongs to the LSM12 family. | 0.627 |
Jpt2 | Lsm2 | ENSMUSP00000024981 | ENSMUSP00000007266 | Jupiter microtubule associated homolog 2. | U6 snRNA-associated Sm-like protein LSm2; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. | 0.438 |
Jpt2 | Mtrex | ENSMUSP00000024981 | ENSMUSP00000022281 | Jupiter microtubule associated homolog 2. | Exosome RNA helicase MTR4; Catalyzes the ATP-dependent unwinding of RNA duplexes with a single-stranded 3' RNA extension. Central subunit of many protein complexes, namely TRAMP-like, nuclear exosome targeting (NEXT) and poly(A) tail exosome targeting (PAXT). NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. PAXT directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental f [...] | 0.503 |
Jpt2 | Rnpepl1 | ENSMUSP00000024981 | ENSMUSP00000027487 | Jupiter microtubule associated homolog 2. | Aminopeptidase RNPEPL1; Broad specificity aminopeptidase which preferentially hydrolyzes an N-terminal methionine, citrulline or glutamine. | 0.535 |
Jpt2 | Tpcn1 | ENSMUSP00000024981 | ENSMUSP00000042188 | Jupiter microtubule associated homolog 2. | Two pore calcium channel protein 1; Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal and endosomal membrane. | 0.522 |
Jpt2 | Tpcn2 | ENSMUSP00000024981 | ENSMUSP00000061308 | Jupiter microtubule associated homolog 2. | Two pore calcium channel protein 2; Nicotinic acid adenine dinucleotide phosphate (NAADP) receptor that may function as one of the major voltage-gated Ca(2+) channels (VDCC) across the lysosomal membrane. Involved in smooth muscle contraction; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. Two pore calcium channel subfamily. | 0.609 |
Jpt2 | Yars | ENSMUSP00000024981 | ENSMUSP00000101669 | Jupiter microtubule associated homolog 2. | Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.598 |
Lsm12 | Jpt2 | ENSMUSP00000021297 | ENSMUSP00000024981 | Protein LSM12 homolog; Belongs to the LSM12 family. | Jupiter microtubule associated homolog 2. | 0.627 |
Lsm12 | Lsm2 | ENSMUSP00000021297 | ENSMUSP00000007266 | Protein LSM12 homolog; Belongs to the LSM12 family. | U6 snRNA-associated Sm-like protein LSm2; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. | 0.623 |
Lsm2 | Jpt2 | ENSMUSP00000007266 | ENSMUSP00000024981 | U6 snRNA-associated Sm-like protein LSm2; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. | Jupiter microtubule associated homolog 2. | 0.438 |
Lsm2 | Lsm12 | ENSMUSP00000007266 | ENSMUSP00000021297 | U6 snRNA-associated Sm-like protein LSm2; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. | Protein LSM12 homolog; Belongs to the LSM12 family. | 0.623 |
Mtrex | Cramp1l | ENSMUSP00000022281 | ENSMUSP00000156906 | Exosome RNA helicase MTR4; Catalyzes the ATP-dependent unwinding of RNA duplexes with a single-stranded 3' RNA extension. Central subunit of many protein complexes, namely TRAMP-like, nuclear exosome targeting (NEXT) and poly(A) tail exosome targeting (PAXT). NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. PAXT directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental f [...] | Protein cramped-like. | 0.562 |
Mtrex | Jpt2 | ENSMUSP00000022281 | ENSMUSP00000024981 | Exosome RNA helicase MTR4; Catalyzes the ATP-dependent unwinding of RNA duplexes with a single-stranded 3' RNA extension. Central subunit of many protein complexes, namely TRAMP-like, nuclear exosome targeting (NEXT) and poly(A) tail exosome targeting (PAXT). NEXT functions as an RNA exosome cofactor that directs a subset of non-coding short-lived RNAs for exosomal degradation. NEXT is involved in surveillance and turnover of aberrant transcripts and non-coding RNAs. PAXT directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental f [...] | Jupiter microtubule associated homolog 2. | 0.503 |