| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ier3ip1 | Yif1a | ENSMUSP00000026487 | ENSMUSP00000025811 | Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus; Belongs to the YOS1 family. | Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi. | 0.418 |
| Ier3ip1 | Yif1b | ENSMUSP00000026487 | ENSMUSP00000032809 | Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus; Belongs to the YOS1 family. | Protein YIF1B; Belongs to the YIF1 family. | 0.414 |
| Ier3ip1 | Yipf5 | ENSMUSP00000026487 | ENSMUSP00000025364 | Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus; Belongs to the YOS1 family. | Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Belongs to the YIP1 family. | 0.717 |
| Manf | Yipf5 | ENSMUSP00000124562 | ENSMUSP00000025364 | Mesencephalic astrocyte-derived neurotrophic factor; Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. Retained in the ER/sarcoplasmic reticulum (SR) through association with the endoplasmic reticulum chaperone protein HSPA5 under normal conditions. Up-regulated and secreted b [...] | Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Belongs to the YIP1 family. | 0.667 |
| Rab1a | Sec23a | ENSMUSP00000127330 | ENSMUSP00000021375 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (By similarity). Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane ; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.647 |
| Rab1a | Sec24b | ENSMUSP00000127330 | ENSMUSP00000001079 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Sec24-related gene family, member B (S. cerevisiae). | 0.763 |
| Rab1a | Yif1a | ENSMUSP00000127330 | ENSMUSP00000025811 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi. | 0.638 |
| Rab1a | Yif1b | ENSMUSP00000127330 | ENSMUSP00000032809 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Protein YIF1B; Belongs to the YIF1 family. | 0.659 |
| Rab1a | Yipf5 | ENSMUSP00000127330 | ENSMUSP00000025364 | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Belongs to the YIP1 family. | 0.666 |
| Sec23a | Rab1a | ENSMUSP00000021375 | ENSMUSP00000127330 | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (By similarity). Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane ; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | 0.647 |
| Sec23a | Sec24b | ENSMUSP00000021375 | ENSMUSP00000001079 | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (By similarity). Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane ; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | Sec24-related gene family, member B (S. cerevisiae). | 0.999 |
| Sec23a | Yipf5 | ENSMUSP00000021375 | ENSMUSP00000025364 | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (By similarity). Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane ; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Belongs to the YIP1 family. | 0.897 |
| Sec24b | Rab1a | ENSMUSP00000001079 | ENSMUSP00000127330 | Sec24-related gene family, member B (S. cerevisiae). | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | 0.763 |
| Sec24b | Sec23a | ENSMUSP00000001079 | ENSMUSP00000021375 | Sec24-related gene family, member B (S. cerevisiae). | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (By similarity). Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane ; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.999 |
| Sec24b | Yipf5 | ENSMUSP00000001079 | ENSMUSP00000025364 | Sec24-related gene family, member B (S. cerevisiae). | Protein YIPF5; Plays a role in transport between endoplasmic reticulum and Golgi; Belongs to the YIP1 family. | 0.892 |
| Yif1a | Ier3ip1 | ENSMUSP00000025811 | ENSMUSP00000026487 | Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi. | Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus; Belongs to the YOS1 family. | 0.418 |
| Yif1a | Rab1a | ENSMUSP00000025811 | ENSMUSP00000127330 | Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi. | Ras-related protein Rab-1A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secreti [...] | 0.638 |
| Yif1a | Yipf1 | ENSMUSP00000025811 | ENSMUSP00000075113 | Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi. | Protein YIPF1; Belongs to the YIP1 family. | 0.663 |
| Yif1a | Yipf2 | ENSMUSP00000025811 | ENSMUSP00000034700 | Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi. | Protein YIPF2; Belongs to the YIP1 family. | 0.704 |
| Yif1a | Yipf3 | ENSMUSP00000025811 | ENSMUSP00000092897 | Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi. | Protein YIPF3, N-terminally processed; Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis (By similarity); Belongs to the YIP1 family. | 0.603 |