STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spink1Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens. (80 aa)    
Predicted Functional Partners:
Prss1
Protease, serine, 1 (Trypsin 1); Belongs to the peptidase S1 family.
    
 
 0.831
2210010C04Rik
RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family.
   
 
 0.822
Prss2
Anionic trypsin-2.
   
 
 0.819
Try5
Trypsinogen 9; Belongs to the peptidase S1 family.
   
 
 0.804
Prss3
Protease, serine 3; Belongs to the peptidase S1 family.
   
 
 0.794
Try4
Pancreatic trypsin; Belongs to the peptidase S1 family.
   
 
 0.789
Try10
Trypsinogen 10; Belongs to the peptidase S1 family.
    
 
 0.772
Gm5771
Predicted gene, EG436523; Belongs to the peptidase S1 family.
    
 
 0.770
Gm10334
Predicted gene 10334; Belongs to the peptidase S1 family.
    
 
 0.770
Ctrc
Chymotrypsin-C; Has chymotrypsin-type protease activity and hypocalcemic activity; Belongs to the peptidase S1 family. Elastase subfamily.
   
 
 0.753
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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