node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dnajb5 | Isoc1 | ENSMUSP00000081712 | ENSMUSP00000025503 | DnaJ homolog subfamily B member 5. | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | 0.522 |
Isoc1 | Dnajb5 | ENSMUSP00000025503 | ENSMUSP00000081712 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | DnaJ homolog subfamily B member 5. | 0.522 |
Isoc1 | Lix1 | ENSMUSP00000025503 | ENSMUSP00000111239 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Protein limb expression 1 homolog; Belongs to the LIX1 family. | 0.584 |
Isoc1 | Matn2 | ENSMUSP00000025503 | ENSMUSP00000022947 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Matrilin-2; Involved in matrix assembly. | 0.458 |
Isoc1 | Nit2 | ENSMUSP00000025503 | ENSMUSP00000023432 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Omega-amidase NIT2; Possesses omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively. Can hydrolyze glutaramate, succinate and gamma- monomethyl-alpha-ketoglutarate in vitro. | 0.527 |
Isoc1 | Olfr530 | ENSMUSP00000025503 | ENSMUSP00000149475 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Olfactory receptor MOR252-2. | 0.526 |
Isoc1 | Pex11b | ENSMUSP00000025503 | ENSMUSP00000113365 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface; Belongs to the peroxin-11 family. | 0.491 |
Isoc1 | Pex3 | ENSMUSP00000025503 | ENSMUSP00000019945 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Peroxisomal biogenesis factor 3; Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes; Belongs to the peroxin-3 family. | 0.469 |
Isoc1 | Plch1 | ENSMUSP00000025503 | ENSMUSP00000081122 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes. | 0.566 |
Isoc1 | Pramef20 | ENSMUSP00000025503 | ENSMUSP00000112488 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | PRAME family member 20. | 0.459 |
Isoc1 | Rasgef1c | ENSMUSP00000025503 | ENSMUSP00000065619 | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | Ras-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF). | 0.556 |
Lix1 | Isoc1 | ENSMUSP00000111239 | ENSMUSP00000025503 | Protein limb expression 1 homolog; Belongs to the LIX1 family. | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | 0.584 |
Lix1 | Plch1 | ENSMUSP00000111239 | ENSMUSP00000081122 | Protein limb expression 1 homolog; Belongs to the LIX1 family. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by calcium-activated phosphatidylinositol-specific phospholipase C enzymes. | 0.472 |
Lix1 | Rasgef1c | ENSMUSP00000111239 | ENSMUSP00000065619 | Protein limb expression 1 homolog; Belongs to the LIX1 family. | Ras-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF). | 0.514 |
Matn2 | Isoc1 | ENSMUSP00000022947 | ENSMUSP00000025503 | Matrilin-2; Involved in matrix assembly. | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | 0.458 |
Nit2 | Isoc1 | ENSMUSP00000023432 | ENSMUSP00000025503 | Omega-amidase NIT2; Possesses omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting 2-oxoglutaramate and 2-oxosuccinamate to biologically useful 2-oxoglutarate and oxaloacetate, respectively. Can hydrolyze glutaramate, succinate and gamma- monomethyl-alpha-ketoglutarate in vitro. | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | 0.527 |
Olfr530 | Isoc1 | ENSMUSP00000149475 | ENSMUSP00000025503 | Olfactory receptor MOR252-2. | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | 0.526 |
Pex11b | Isoc1 | ENSMUSP00000113365 | ENSMUSP00000025503 | Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface; Belongs to the peroxin-11 family. | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | 0.491 |
Pex11b | Pex3 | ENSMUSP00000113365 | ENSMUSP00000019945 | Peroxisomal membrane protein 11B; Involved in peroxisomal proliferation. May regulate peroxisome division by recruiting the dynamin-related GTPase DNM1L to the peroxisomal membrane. Promotes membrane protrusion and elongation on the peroxisomal surface; Belongs to the peroxin-11 family. | Peroxisomal biogenesis factor 3; Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes; Belongs to the peroxin-3 family. | 0.788 |
Pex3 | Isoc1 | ENSMUSP00000019945 | ENSMUSP00000025503 | Peroxisomal biogenesis factor 3; Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes; Belongs to the peroxin-3 family. | Isochorismatase domain-containing protein 1; Belongs to the isochorismatase family. | 0.469 |