node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ccdc86 | Ccdc96 | ENSMUSP00000025639 | ENSMUSP00000059636 | Coiled-coil domain-containing protein 86. | Coiled-coil domain-containing protein 96. | 0.540 |
Ccdc86 | Etfa | ENSMUSP00000025639 | ENSMUSP00000034866 | Coiled-coil domain-containing protein 86. | Electron transfer flavoprotein subunit alpha, mitochondrial; Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF- ubiquinone oxidoreductase (ETF dehydrogenase). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. | 0.534 |
Ccdc86 | Gm17657 | ENSMUSP00000025639 | ENSMUSP00000157004 | Coiled-coil domain-containing protein 86. | Predicted gene, 17657. | 0.478 |
Ccdc86 | Grwd1 | ENSMUSP00000025639 | ENSMUSP00000116252 | Coiled-coil domain-containing protein 86. | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | 0.552 |
Ccdc86 | Lyar | ENSMUSP00000025639 | ENSMUSP00000084791 | Coiled-coil domain-containing protein 86. | Cell growth-regulating nucleolar protein; Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (By similarity). Also acts at the level of transcription regulation. Along with PRMT5, binds embryonic globin promoter (By similarity). Represses the expression of embryonic globin Hbb-y gene. In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and that encoding the small nucleolar RNA SNORD41 (By similarity). Pref [...] | 0.635 |
Ccdc86 | Mrto4 | ENSMUSP00000025639 | ENSMUSP00000099561 | Coiled-coil domain-containing protein 86. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.704 |
Ccdc86 | Nip7 | ENSMUSP00000025639 | ENSMUSP00000034392 | Coiled-coil domain-containing protein 86. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. | 0.640 |
Ccdc86 | Rrp9 | ENSMUSP00000025639 | ENSMUSP00000038580 | Coiled-coil domain-containing protein 86. | U3 small nucleolar RNA-interacting protein 2; Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (pre-rRNA). | 0.555 |
Ccdc86 | Tm2d1 | ENSMUSP00000025639 | ENSMUSP00000099855 | Coiled-coil domain-containing protein 86. | TM2 domain-containing protein 1; May participate in amyloid-beta-induced apoptosis via its interaction with beta-APP42. | 0.520 |
Ccdc86 | Vkorc1l1 | ENSMUSP00000025639 | ENSMUSP00000059139 | Coiled-coil domain-containing protein 86. | Vitamin K epoxide reductase complex subunit 1-like protein 1; Involved in vitamin K metabolism. Can reduce inactive vitamin K 2,3-epoxide to active vitamin K (in vitro), and may contribute to vitamin K-mediated protection against oxidative stress. Plays a role in vitamin K-dependent gamma-carboxylation of Glu residues in target proteins; Belongs to the VKOR family. | 0.592 |
Ccdc96 | Ccdc86 | ENSMUSP00000059636 | ENSMUSP00000025639 | Coiled-coil domain-containing protein 96. | Coiled-coil domain-containing protein 86. | 0.540 |
Etfa | Ccdc86 | ENSMUSP00000034866 | ENSMUSP00000025639 | Electron transfer flavoprotein subunit alpha, mitochondrial; Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF- ubiquinone oxidoreductase (ETF dehydrogenase). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism. | Coiled-coil domain-containing protein 86. | 0.534 |
Gm17657 | Ccdc86 | ENSMUSP00000157004 | ENSMUSP00000025639 | Predicted gene, 17657. | Coiled-coil domain-containing protein 86. | 0.478 |
Grwd1 | Ccdc86 | ENSMUSP00000116252 | ENSMUSP00000025639 | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | Coiled-coil domain-containing protein 86. | 0.552 |
Grwd1 | Lyar | ENSMUSP00000116252 | ENSMUSP00000084791 | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | Cell growth-regulating nucleolar protein; Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (By similarity). Also acts at the level of transcription regulation. Along with PRMT5, binds embryonic globin promoter (By similarity). Represses the expression of embryonic globin Hbb-y gene. In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and that encoding the small nucleolar RNA SNORD41 (By similarity). Pref [...] | 0.808 |
Grwd1 | Mrto4 | ENSMUSP00000116252 | ENSMUSP00000099561 | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.954 |
Grwd1 | Nip7 | ENSMUSP00000116252 | ENSMUSP00000034392 | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. | 0.908 |
Grwd1 | Rrp9 | ENSMUSP00000116252 | ENSMUSP00000038580 | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | U3 small nucleolar RNA-interacting protein 2; Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (pre-rRNA). | 0.945 |
Lyar | Ccdc86 | ENSMUSP00000084791 | ENSMUSP00000025639 | Cell growth-regulating nucleolar protein; Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (By similarity). Also acts at the level of transcription regulation. Along with PRMT5, binds embryonic globin promoter (By similarity). Represses the expression of embryonic globin Hbb-y gene. In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and that encoding the small nucleolar RNA SNORD41 (By similarity). Pref [...] | Coiled-coil domain-containing protein 86. | 0.635 |
Lyar | Grwd1 | ENSMUSP00000084791 | ENSMUSP00000116252 | Cell growth-regulating nucleolar protein; Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (By similarity). Also acts at the level of transcription regulation. Along with PRMT5, binds embryonic globin promoter (By similarity). Represses the expression of embryonic globin Hbb-y gene. In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and that encoding the small nucleolar RNA SNORD41 (By similarity). Pref [...] | Glutamate-rich WD repeat-containing protein 1; Histone binding-protein that regulates chromatin dynamics and minichromosome maintenance (MCM) loading at replication origins, possibly by promoting chromatin openness. | 0.808 |