| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Acr | Tesmin | ENSMUSP00000023295 | ENSMUSP00000025840 | Acrosin heavy chain; Acrosin is the major protease of mammalian spermatozoa. It is a serine protease of trypsin-like cleavage specificity, it is synthesized in a zymogen form, proacrosin and stored in the acrosome; Belongs to the peptidase S1 family. | Tesmin; May have a role in spermatogenesis. | 0.598 |
| Lin37 | Lin52 | ENSMUSP00000048557 | ENSMUSP00000133045 | Protein lin-37 homolog. | Protein lin-52 homolog. | 0.999 |
| Lin37 | Lin9 | ENSMUSP00000048557 | ENSMUSP00000141331 | Protein lin-37 homolog. | Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition (By similarity); Belongs to the lin-9 family. | 0.999 |
| Lin37 | Rbbp4 | ENSMUSP00000048557 | ENSMUSP00000099658 | Protein lin-37 homolog. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | 0.999 |
| Lin37 | Rbbp7 | ENSMUSP00000048557 | ENSMUSP00000033720 | Protein lin-37 homolog. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.854 |
| Lin37 | Tesmin | ENSMUSP00000048557 | ENSMUSP00000025840 | Protein lin-37 homolog. | Tesmin; May have a role in spermatogenesis. | 0.731 |
| Lin52 | Lin37 | ENSMUSP00000133045 | ENSMUSP00000048557 | Protein lin-52 homolog. | Protein lin-37 homolog. | 0.999 |
| Lin52 | Lin9 | ENSMUSP00000133045 | ENSMUSP00000141331 | Protein lin-52 homolog. | Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition (By similarity); Belongs to the lin-9 family. | 0.999 |
| Lin52 | Rbbp4 | ENSMUSP00000133045 | ENSMUSP00000099658 | Protein lin-52 homolog. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | 0.999 |
| Lin52 | Rbbp7 | ENSMUSP00000133045 | ENSMUSP00000033720 | Protein lin-52 homolog. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.778 |
| Lin52 | Tesmin | ENSMUSP00000133045 | ENSMUSP00000025840 | Protein lin-52 homolog. | Tesmin; May have a role in spermatogenesis. | 0.861 |
| Lin52 | Tmem147 | ENSMUSP00000133045 | ENSMUSP00000006478 | Protein lin-52 homolog. | Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). | 0.637 |
| Lin52 | Wdr73 | ENSMUSP00000133045 | ENSMUSP00000026816 | Protein lin-52 homolog. | WD repeat-containing protein 73; May play a role in the regulation of microtubule organization and dynamics. | 0.565 |
| Lin9 | Lin37 | ENSMUSP00000141331 | ENSMUSP00000048557 | Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition (By similarity); Belongs to the lin-9 family. | Protein lin-37 homolog. | 0.999 |
| Lin9 | Lin52 | ENSMUSP00000141331 | ENSMUSP00000133045 | Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition (By similarity); Belongs to the lin-9 family. | Protein lin-52 homolog. | 0.999 |
| Lin9 | Rbbp4 | ENSMUSP00000141331 | ENSMUSP00000099658 | Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition (By similarity); Belongs to the lin-9 family. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | 0.999 |
| Lin9 | Rbbp7 | ENSMUSP00000141331 | ENSMUSP00000033720 | Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition (By similarity); Belongs to the lin-9 family. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.879 |
| Lin9 | Tesmin | ENSMUSP00000141331 | ENSMUSP00000025840 | Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition (By similarity); Belongs to the lin-9 family. | Tesmin; May have a role in spermatogenesis. | 0.852 |
| Lin9 | Tmem147 | ENSMUSP00000141331 | ENSMUSP00000006478 | Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition (By similarity); Belongs to the lin-9 family. | Transmembrane protein 147; Acts as a negative regulator of CHRM3 function, most likely by interfering with its trafficking to the cell membrane (By similarity). Negatively regulates CHRM3-mediated calcium mobilization and activation of RPS6KA1/p90RSK activity (By similarity). | 0.617 |
| Lin9 | Wdr73 | ENSMUSP00000141331 | ENSMUSP00000026816 | Protein lin-9 homolog; Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition (By similarity); Belongs to the lin-9 family. | WD repeat-containing protein 73; May play a role in the regulation of microtubule organization and dynamics. | 0.772 |