| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Gns | Gusb | ENSMUSP00000043167 | ENSMUSP00000026613 | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | 0.966 |
| Gusb | Gns | ENSMUSP00000026613 | ENSMUSP00000043167 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | N-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. | 0.966 |
| Gusb | Kl | ENSMUSP00000026613 | ENSMUSP00000077899 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1; Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. | 0.954 |
| Gusb | Ugt1a5 | ENSMUSP00000026613 | ENSMUSP00000095263 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.946 |
| Gusb | Ugt1a6b | ENSMUSP00000026613 | ENSMUSP00000108763 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.946 |
| Gusb | Ugt2a3 | ENSMUSP00000026613 | ENSMUSP00000031195 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | UDP-glucuronosyltransferase 2A3; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.951 |
| Gusb | Ugt2b1 | ENSMUSP00000026613 | ENSMUSP00000031183 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.946 |
| Gusb | Ugt2b34 | ENSMUSP00000026613 | ENSMUSP00000031181 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.948 |
| Gusb | Ugt2b35 | ENSMUSP00000026613 | ENSMUSP00000031186 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.946 |
| Gusb | Ugt2b36 | ENSMUSP00000026613 | ENSMUSP00000092233 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.946 |
| Gusb | Ugt2b37 | ENSMUSP00000026613 | ENSMUSP00000075255 | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.946 |
| Kl | Gusb | ENSMUSP00000077899 | ENSMUSP00000026613 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1; Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. | Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates. | 0.954 |
| Kl | Ugt1a5 | ENSMUSP00000077899 | ENSMUSP00000095263 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1; Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.658 |
| Kl | Ugt1a6b | ENSMUSP00000077899 | ENSMUSP00000108763 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1; Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.658 |
| Kl | Ugt2a3 | ENSMUSP00000077899 | ENSMUSP00000031195 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1; Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. | UDP-glucuronosyltransferase 2A3; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family. | 0.658 |
| Kl | Ugt2b1 | ENSMUSP00000077899 | ENSMUSP00000031183 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1; Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.658 |
| Kl | Ugt2b34 | ENSMUSP00000077899 | ENSMUSP00000031181 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1; Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.658 |
| Kl | Ugt2b35 | ENSMUSP00000077899 | ENSMUSP00000031186 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1; Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.658 |
| Kl | Ugt2b36 | ENSMUSP00000077899 | ENSMUSP00000092233 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1; Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.658 |
| Kl | Ugt2b37 | ENSMUSP00000077899 | ENSMUSP00000075255 | Klotho peptide; May have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 241 and 874, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1; Belongs to the glycosyl hydrolase 1 family. Klotho subfamily. | UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. | 0.659 |