Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A830018L16Rik | Msc | ENSMUSP00000117421 | ENSMUSP00000027062 | Uncharacterized protein C8orf34 homolog. | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | 0.459 |
| Hes6 | Msc | ENSMUSP00000084062 | ENSMUSP00000027062 | Transcription cofactor HES-6; Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up- regulate transcription in its presence. Promotes cell differentiation. | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | 0.467 |
| Msc | A830018L16Rik | ENSMUSP00000027062 | ENSMUSP00000117421 | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | Uncharacterized protein C8orf34 homolog. | 0.459 |
| Msc | Hes6 | ENSMUSP00000027062 | ENSMUSP00000084062 | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | Transcription cofactor HES-6; Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up- regulate transcription in its presence. Promotes cell differentiation. | 0.467 |
| Msc | Myf5 | ENSMUSP00000027062 | ENSMUSP00000000445 | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | 0.565 |
| Msc | Myf6 | ENSMUSP00000027062 | ENSMUSP00000047529 | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | 0.491 |
| Msc | Myod1 | ENSMUSP00000027062 | ENSMUSP00000072330 | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins. | 0.655 |
| Msc | Myog | ENSMUSP00000027062 | ENSMUSP00000027730 | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...] | 0.536 |
| Msc | Pax3 | ENSMUSP00000027062 | ENSMUSP00000004994 | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | Paired box protein Pax-3; Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10 (By similarity); Belongs to the paired homeobox family. | 0.495 |
| Msc | Pax7 | ENSMUSP00000027062 | ENSMUSP00000030508 | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | Paired box protein Pax-7; Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation. Belongs to the paired homeobox family. | 0.496 |
| Msc | Pitx2 | ENSMUSP00000027062 | ENSMUSP00000047359 | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | Pituitary homeobox 2; Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform Ptx2c is involved in left-right asymmetry the developing embryo. | 0.493 |
| Msc | Zbtb49 | ENSMUSP00000027062 | ENSMUSP00000092429 | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | Zinc finger and BTB domain-containing protein 49; Transcription factor. Inhibits cell proliferation by activating either CDKN1A/p21 transcription or RB1 transcription. | 0.536 |
| Myf5 | Msc | ENSMUSP00000000445 | ENSMUSP00000027062 | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | 0.565 |
| Myf5 | Myf6 | ENSMUSP00000000445 | ENSMUSP00000047529 | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | 0.885 |
| Myf5 | Myod1 | ENSMUSP00000000445 | ENSMUSP00000072330 | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins. | 0.532 |
| Myf5 | Myog | ENSMUSP00000000445 | ENSMUSP00000027730 | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...] | 0.693 |
| Myf5 | Pax3 | ENSMUSP00000000445 | ENSMUSP00000004994 | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | Paired box protein Pax-3; Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis. Transcriptional activator of MITF, acting synergistically with SOX10 (By similarity); Belongs to the paired homeobox family. | 0.874 |
| Myf5 | Pax7 | ENSMUSP00000000445 | ENSMUSP00000030508 | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | Paired box protein Pax-7; Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation. Belongs to the paired homeobox family. | 0.906 |
| Myf5 | Pitx2 | ENSMUSP00000000445 | ENSMUSP00000047359 | Myogenic factor 5; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYOG and MYOD1, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | Pituitary homeobox 2; Controls cell proliferation in a tissue-specific manner and is involved in morphogenesis. During embryonic development, exerts a role in the expansion of muscle progenitors. May play a role in the proper localization of asymmetric organs such as the heart and stomach. Isoform Ptx2c is involved in left-right asymmetry the developing embryo. | 0.565 |
| Myf6 | Msc | ENSMUSP00000047529 | ENSMUSP00000027062 | Myogenic factor 6; Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. | Musculin; Transcription repressor that blocks myogenesis and activation of E-box dependent muscle genes. | 0.491 |
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