STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PnkdProbable hydrolase PNKD; Probable hydrolase that plays an aggravative role in the development of cardiac hypertrophy via activation of the NF-kappa-B signaling pathway. (385 aa)    
Predicted Functional Partners:
Tmem230
Transmembrane protein 230; Involved in trafficking and recycling of synaptic vesicles.
   
 
 0.660
Slc35d3
Solute carrier family 35 member D3; May play a role in hemostasis as a regulator of the biosynthesis of platelet-dense granules.
      
 0.629
Suox
Sulfite oxidase, mitochondrial.
   
  
 0.559
Pgghg
Protein-glucosylgalactosylhydroxylysine glucosidase; Catalyzes the hydrolysis of glucose from the disaccharide unit linked to hydroxylysine residues of collagen and collagen-like proteins.
   
  
 0.542
Pet100
Protein PET100 homolog, mitochondrial; Belongs to the PET100 family.
   
  
 0.463
Pet117
Protein PET117 homolog, mitochondrial.
      
 0.463
Asic4
Acid-sensing ion channel 4; Probable cation channel with high affinity for sodium; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily.
      
 0.456
Tmem143
Transmembrane protein 143.
   
  
 0.452
Ybey
Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation; Belongs to the endoribonuclease YbeY family.
  
 
 0.439
Tstd3
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3.
  
 
 0.438
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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