node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Csta1 | Ctsl | ENSMUSP00000093795 | ENSMUSP00000152169 | Cystatin-A; This is an intracellular thiol proteinase inhibitor. Belongs to the cystatin family. | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Belongs to the peptidase C1 family. | 0.685 |
Csta1 | Serpinb13 | ENSMUSP00000093795 | ENSMUSP00000027564 | Cystatin-A; This is an intracellular thiol proteinase inhibitor. Belongs to the cystatin family. | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | 0.401 |
Ctsg | Ctsk | ENSMUSP00000015583 | ENSMUSP00000015664 | Cathepsin G; This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis. | Cathepsin K; Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen ; Belongs to the peptidase C1 family. | 0.457 |
Ctsg | Ctsl | ENSMUSP00000015583 | ENSMUSP00000152169 | Cathepsin G; This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis. | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Belongs to the peptidase C1 family. | 0.525 |
Ctsg | Serpinb13 | ENSMUSP00000015583 | ENSMUSP00000027564 | Cathepsin G; This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis. | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | 0.924 |
Ctsk | Ctsg | ENSMUSP00000015664 | ENSMUSP00000015583 | Cathepsin K; Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen ; Belongs to the peptidase C1 family. | Cathepsin G; This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis. | 0.457 |
Ctsk | Ctsl | ENSMUSP00000015664 | ENSMUSP00000152169 | Cathepsin K; Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen ; Belongs to the peptidase C1 family. | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Belongs to the peptidase C1 family. | 0.744 |
Ctsk | Serpinb13 | ENSMUSP00000015664 | ENSMUSP00000027564 | Cathepsin K; Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen ; Belongs to the peptidase C1 family. | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | 0.919 |
Ctsl | Csta1 | ENSMUSP00000152169 | ENSMUSP00000093795 | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Belongs to the peptidase C1 family. | Cystatin-A; This is an intracellular thiol proteinase inhibitor. Belongs to the cystatin family. | 0.685 |
Ctsl | Ctsg | ENSMUSP00000152169 | ENSMUSP00000015583 | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Belongs to the peptidase C1 family. | Cathepsin G; This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis. | 0.525 |
Ctsl | Ctsk | ENSMUSP00000152169 | ENSMUSP00000015664 | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Belongs to the peptidase C1 family. | Cathepsin K; Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen ; Belongs to the peptidase C1 family. | 0.744 |
Ctsl | Serpinb13 | ENSMUSP00000152169 | ENSMUSP00000027564 | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Belongs to the peptidase C1 family. | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | 0.942 |
Insyn2b | Serpinb13 | ENSMUSP00000129183 | ENSMUSP00000027564 | INSYN2B protein; Belongs to the INSYN2 family. | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | 0.422 |
Klk14 | Serpinb13 | ENSMUSP00000056935 | ENSMUSP00000027564 | Kallikrein-14; Serine-type endopeptidase with a dual trypsin-like and chymotrypsin-like substrate specificity. May activate/inactivate the proteinase-activated receptors F2R, F2RL1 and F2RL3 and other kallikreins including KLK1, KLK3, KLK5 and KLK11. May function in seminal clot liquefaction through direct cleavage of the semenogelin SEMG1 and SEMG2 and activation of KLK3. May function through desmoglein DSG1 cleavage in epidermal desquamation a process by which the most superficial corneocytes are shed from the skin surface. May be involved in several aspects of tumor progression incl [...] | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | 0.407 |
Klk5 | Serpinb13 | ENSMUSP00000049339 | ENSMUSP00000027564 | Kallikrein-related-peptidase 5; Belongs to the peptidase S1 family. | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | 0.436 |
Klk6 | Serpinb13 | ENSMUSP00000103602 | ENSMUSP00000027564 | Kallikrein-related-peptidase 6; Belongs to the peptidase S1 family. | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | 0.508 |
Serpinb13 | Csta1 | ENSMUSP00000027564 | ENSMUSP00000093795 | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | Cystatin-A; This is an intracellular thiol proteinase inhibitor. Belongs to the cystatin family. | 0.401 |
Serpinb13 | Ctsg | ENSMUSP00000027564 | ENSMUSP00000015583 | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | Cathepsin G; This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis. | 0.924 |
Serpinb13 | Ctsk | ENSMUSP00000027564 | ENSMUSP00000015664 | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | Cathepsin K; Thiol protease involved in osteoclastic bone resorption. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen ; Belongs to the peptidase C1 family. | 0.919 |
Serpinb13 | Ctsl | ENSMUSP00000027564 | ENSMUSP00000152169 | Serpin B13; May play a role in the proliferation or differentiation of keratinocytes. | Cathepsin L1 heavy chain; Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. Belongs to the peptidase C1 family. | 0.942 |