Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Afap1l1 | Cttn | ENSMUSP00000113286 | ENSMUSP00000099368 | Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation. | Src substrate cortactin; Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration (By similarity). Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in the invasiveness of cancer cells, and the formation of metastases (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and M [...] | 0.588 |
| Afap1l1 | Hcls1 | ENSMUSP00000113286 | ENSMUSP00000023531 | Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation. | Hematopoietic lineage cell-specific protein; Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression (By similarity). | 0.589 |
| Afap1l1 | Plxdc2 | ENSMUSP00000113286 | ENSMUSP00000028081 | Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation. | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | 0.441 |
| Afap1l1 | Sparcl1 | ENSMUSP00000113286 | ENSMUSP00000031249 | Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation. | SPARC-like protein 1; Belongs to the SPARC family. | 0.553 |
| Cttn | Afap1l1 | ENSMUSP00000099368 | ENSMUSP00000113286 | Src substrate cortactin; Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration (By similarity). Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in the invasiveness of cancer cells, and the formation of metastases (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and M [...] | Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation. | 0.588 |
| Cttn | Hcls1 | ENSMUSP00000099368 | ENSMUSP00000023531 | Src substrate cortactin; Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration (By similarity). Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in the invasiveness of cancer cells, and the formation of metastases (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and M [...] | Hematopoietic lineage cell-specific protein; Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression (By similarity). | 0.913 |
| Cttn | Plxdc2 | ENSMUSP00000099368 | ENSMUSP00000028081 | Src substrate cortactin; Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration (By similarity). Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in the invasiveness of cancer cells, and the formation of metastases (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and M [...] | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | 0.527 |
| Etl4 | Plxdc2 | ENSMUSP00000110274 | ENSMUSP00000028081 | Sickle tail protein; Required for normal development of intervertebral disks. | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | 0.529 |
| Hcls1 | Afap1l1 | ENSMUSP00000023531 | ENSMUSP00000113286 | Hematopoietic lineage cell-specific protein; Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression (By similarity). | Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation. | 0.589 |
| Hcls1 | Cttn | ENSMUSP00000023531 | ENSMUSP00000099368 | Hematopoietic lineage cell-specific protein; Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression (By similarity). | Src substrate cortactin; Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration (By similarity). Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in the invasiveness of cancer cells, and the formation of metastases (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and M [...] | 0.913 |
| Hcls1 | Plxdc2 | ENSMUSP00000023531 | ENSMUSP00000028081 | Hematopoietic lineage cell-specific protein; Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression (By similarity). | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | 0.528 |
| Klhl25 | Plxdc2 | ENSMUSP00000133175 | ENSMUSP00000028081 | Kelch-like protein 25; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E. | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | 0.501 |
| Nrep | Plxdc2 | ENSMUSP00000127787 | ENSMUSP00000028081 | Neuronal regeneration-related protein; May have roles in cellular differentiation. Ectopic expression induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis. May also have neural functions. Promotes axonal regeneration and augments motility of gliomas. Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3. May play a role in the regulation of alveolar generation. | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | 0.443 |
| Plxdc2 | Afap1l1 | ENSMUSP00000028081 | ENSMUSP00000113286 | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation. | 0.441 |
| Plxdc2 | Cttn | ENSMUSP00000028081 | ENSMUSP00000099368 | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | Src substrate cortactin; Contributes to the organization of the actin cytoskeleton and cell shape. Plays a role in the formation of lamellipodia and in cell migration (By similarity). Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density. Plays a role in the invasiveness of cancer cells, and the formation of metastases (By similarity). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and M [...] | 0.527 |
| Plxdc2 | Etl4 | ENSMUSP00000028081 | ENSMUSP00000110274 | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | Sickle tail protein; Required for normal development of intervertebral disks. | 0.529 |
| Plxdc2 | Hcls1 | ENSMUSP00000028081 | ENSMUSP00000023531 | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | Hematopoietic lineage cell-specific protein; Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. May also be involved in the regulation of gene expression (By similarity). | 0.528 |
| Plxdc2 | Klhl25 | ENSMUSP00000028081 | ENSMUSP00000133175 | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | Kelch-like protein 25; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E. | 0.501 |
| Plxdc2 | Nrep | ENSMUSP00000028081 | ENSMUSP00000127787 | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | Neuronal regeneration-related protein; May have roles in cellular differentiation. Ectopic expression induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis. May also have neural functions. Promotes axonal regeneration and augments motility of gliomas. Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3. May play a role in the regulation of alveolar generation. | 0.443 |
| Plxdc2 | Rbm6 | ENSMUSP00000028081 | ENSMUSP00000138400 | Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family. | RNA-binding motif protein 6. | 0.472 |
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