node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Angel2 | Arl6ip6 | ENSMUSP00000064556 | ENSMUSP00000028336 | Protein angel homolog 2. | ADP-ribosylation factor-like protein 6-interacting protein 6. | 0.502 |
Arl6ip6 | Angel2 | ENSMUSP00000028336 | ENSMUSP00000064556 | ADP-ribosylation factor-like protein 6-interacting protein 6. | Protein angel homolog 2. | 0.502 |
Arl6ip6 | Fmnl2 | ENSMUSP00000028336 | ENSMUSP00000047260 | ADP-ribosylation factor-like protein 6-interacting protein 6. | Formin-like protein 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics (By similarity); Belongs to the formin homology family. | 0.625 |
Arl6ip6 | Med29 | ENSMUSP00000028336 | ENSMUSP00000003536 | ADP-ribosylation factor-like protein 6-interacting protein 6. | Mediator of RNA polymerase II transcription subunit 29; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.644 |
Arl6ip6 | Mrps9 | ENSMUSP00000028336 | ENSMUSP00000056855 | ADP-ribosylation factor-like protein 6-interacting protein 6. | 28S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family. | 0.535 |
Arl6ip6 | N6amt1 | ENSMUSP00000028336 | ENSMUSP00000061835 | ADP-ribosylation factor-like protein 6-interacting protein 6. | Methyltransferase N6AMT1; Methyltransferase that can methylate both proteins and DNA, and to a lower extent, arsenic. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5- methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif. Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. Also acts as a N(6)-adenine- specific DNA methyltransferase by mediating methylation of DNA on the 6th position of adenine (N(6)-methyladenosine) (By similarity). N(6)- methyladenosine (m6A) DNA is significantly [...] | 0.588 |
Arl6ip6 | Plbd2 | ENSMUSP00000028336 | ENSMUSP00000031597 | ADP-ribosylation factor-like protein 6-interacting protein 6. | Putative phospholipase B-like 2 15 kDa form; Putative phospholipase. | 0.582 |
Arl6ip6 | Rftn2 | ENSMUSP00000028336 | ENSMUSP00000027121 | ADP-ribosylation factor-like protein 6-interacting protein 6. | Raftlin-2; Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling. | 0.618 |
Arl6ip6 | Rnase13 | ENSMUSP00000028336 | ENSMUSP00000087203 | ADP-ribosylation factor-like protein 6-interacting protein 6. | Probable inactive ribonuclease-like protein 13; Does not exhibit any ribonuclease activity; Belongs to the pancreatic ribonuclease family. | 0.520 |
Arl6ip6 | Rnf122 | ENSMUSP00000028336 | ENSMUSP00000040478 | ADP-ribosylation factor-like protein 6-interacting protein 6. | RING finger protein 122; May induce necrosis and apoptosis. May play a role in cell viability (By similarity). | 0.523 |
Arl6ip6 | Zfp35 | ENSMUSP00000028336 | ENSMUSP00000074475 | ADP-ribosylation factor-like protein 6-interacting protein 6. | Zinc finger protein 271; May act to control gene activity during the pachytene stage of meiotic prophase. May function as a transcription activator. | 0.540 |
Fmnl2 | Arl6ip6 | ENSMUSP00000047260 | ENSMUSP00000028336 | Formin-like protein 2; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics (By similarity); Belongs to the formin homology family. | ADP-ribosylation factor-like protein 6-interacting protein 6. | 0.625 |
Med29 | Arl6ip6 | ENSMUSP00000003536 | ENSMUSP00000028336 | Mediator of RNA polymerase II transcription subunit 29; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | ADP-ribosylation factor-like protein 6-interacting protein 6. | 0.644 |
Mrps9 | Arl6ip6 | ENSMUSP00000056855 | ENSMUSP00000028336 | 28S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family. | ADP-ribosylation factor-like protein 6-interacting protein 6. | 0.535 |
Mrps9 | Rnf122 | ENSMUSP00000056855 | ENSMUSP00000040478 | 28S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family. | RING finger protein 122; May induce necrosis and apoptosis. May play a role in cell viability (By similarity). | 0.474 |
N6amt1 | Arl6ip6 | ENSMUSP00000061835 | ENSMUSP00000028336 | Methyltransferase N6AMT1; Methyltransferase that can methylate both proteins and DNA, and to a lower extent, arsenic. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5- methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif. Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. Also acts as a N(6)-adenine- specific DNA methyltransferase by mediating methylation of DNA on the 6th position of adenine (N(6)-methyladenosine) (By similarity). N(6)- methyladenosine (m6A) DNA is significantly [...] | ADP-ribosylation factor-like protein 6-interacting protein 6. | 0.588 |
N6amt1 | Plbd2 | ENSMUSP00000061835 | ENSMUSP00000031597 | Methyltransferase N6AMT1; Methyltransferase that can methylate both proteins and DNA, and to a lower extent, arsenic. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5- methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif. Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. Also acts as a N(6)-adenine- specific DNA methyltransferase by mediating methylation of DNA on the 6th position of adenine (N(6)-methyladenosine) (By similarity). N(6)- methyladenosine (m6A) DNA is significantly [...] | Putative phospholipase B-like 2 15 kDa form; Putative phospholipase. | 0.515 |
N6amt1 | Rftn2 | ENSMUSP00000061835 | ENSMUSP00000027121 | Methyltransferase N6AMT1; Methyltransferase that can methylate both proteins and DNA, and to a lower extent, arsenic. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5- methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif. Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. Also acts as a N(6)-adenine- specific DNA methyltransferase by mediating methylation of DNA on the 6th position of adenine (N(6)-methyladenosine) (By similarity). N(6)- methyladenosine (m6A) DNA is significantly [...] | Raftlin-2; Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling. | 0.553 |
Plbd2 | Arl6ip6 | ENSMUSP00000031597 | ENSMUSP00000028336 | Putative phospholipase B-like 2 15 kDa form; Putative phospholipase. | ADP-ribosylation factor-like protein 6-interacting protein 6. | 0.582 |
Plbd2 | N6amt1 | ENSMUSP00000031597 | ENSMUSP00000061835 | Putative phospholipase B-like 2 15 kDa form; Putative phospholipase. | Methyltransferase N6AMT1; Methyltransferase that can methylate both proteins and DNA, and to a lower extent, arsenic. Catalytic subunit of a heterodimer with TRMT112, which catalyzes N5- methylation of Glu residue of proteins with a Gly-Gln-Xaa-Xaa-Xaa-Arg motif. Methylates ETF1 on 'Gln-185'; ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. Also acts as a N(6)-adenine- specific DNA methyltransferase by mediating methylation of DNA on the 6th position of adenine (N(6)-methyladenosine) (By similarity). N(6)- methyladenosine (m6A) DNA is significantly [...] | 0.515 |