| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Chrna10 | Otor | ENSMUSP00000081891 | ENSMUSP00000028902 | Cholinergic receptor, nicotinic, alpha polypeptide 10. | Otoraplin; Belongs to the MIA/OTOR family. | 0.507 |
| Cldn17 | Otor | ENSMUSP00000066427 | ENSMUSP00000028902 | Claudin-17; Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability; Belongs to the claudin family. | Otoraplin; Belongs to the MIA/OTOR family. | 0.550 |
| Hacd2 | Otor | ENSMUSP00000060462 | ENSMUSP00000028902 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursor [...] | Otoraplin; Belongs to the MIA/OTOR family. | 0.503 |
| Otor | Chrna10 | ENSMUSP00000028902 | ENSMUSP00000081891 | Otoraplin; Belongs to the MIA/OTOR family. | Cholinergic receptor, nicotinic, alpha polypeptide 10. | 0.507 |
| Otor | Cldn17 | ENSMUSP00000028902 | ENSMUSP00000066427 | Otoraplin; Belongs to the MIA/OTOR family. | Claudin-17; Channel-forming tight junction protein with selectivity for anions, including chloride and bicarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in quantitative reabsorption of filtered anions. Does not affect water permeability; Belongs to the claudin family. | 0.550 |
| Otor | Hacd2 | ENSMUSP00000028902 | ENSMUSP00000060462 | Otoraplin; Belongs to the MIA/OTOR family. | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursor [...] | 0.503 |
| Otor | Sebox | ENSMUSP00000028902 | ENSMUSP00000001130 | Otoraplin; Belongs to the MIA/OTOR family. | Homeobox protein SEBOX; Probable transcription factor involved in the control of specification of mesoderm and endoderm; Belongs to the paired homeobox family. | 0.408 |
| Otor | Slc46a2 | ENSMUSP00000028902 | ENSMUSP00000030081 | Otoraplin; Belongs to the MIA/OTOR family. | Thymic stromal cotransporter protein; May act as a transporter. | 0.495 |
| Otor | Snx3 | ENSMUSP00000028902 | ENSMUSP00000019939 | Otoraplin; Belongs to the MIA/OTOR family. | Sorting nexin-3; Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Also can bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2). Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome membrane association of the retromer cargo-selective subcomplex (CSC). May act in part as component of the SNX3-retromer complex which mediates the retrograde en [...] | 0.453 |
| Otor | Spag4 | ENSMUSP00000028902 | ENSMUSP00000036484 | Otoraplin; Belongs to the MIA/OTOR family. | Sperm-associated antigen 4 protein; Involved in spermatogenesis. Required for sperm head formation but not required to establish and maintain general polarity of the sperm head. Required for anchoring and organization of the manchette. Required for targeting of SUN3 and probably SYNE1 through a probable SUN1:SYNE3 LINC complex to the nuclear envelope and involved in accurate posterior sperm head localization of the complex. May anchor SUN3 the nuclear envelope. Involved in maintenance of the nuclear envelope integrity. May assist the organization and assembly of outer dense fibers (ODF [...] | 0.489 |
| Otor | Ucma | ENSMUSP00000028902 | ENSMUSP00000110662 | Otoraplin; Belongs to the MIA/OTOR family. | Unique cartilage matrix-associated protein C-terminal fragment; May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. Belongs to the UCMA family. | 0.491 |
| Sebox | Otor | ENSMUSP00000001130 | ENSMUSP00000028902 | Homeobox protein SEBOX; Probable transcription factor involved in the control of specification of mesoderm and endoderm; Belongs to the paired homeobox family. | Otoraplin; Belongs to the MIA/OTOR family. | 0.408 |
| Slc46a2 | Otor | ENSMUSP00000030081 | ENSMUSP00000028902 | Thymic stromal cotransporter protein; May act as a transporter. | Otoraplin; Belongs to the MIA/OTOR family. | 0.495 |
| Snx3 | Otor | ENSMUSP00000019939 | ENSMUSP00000028902 | Sorting nexin-3; Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Also can bind phosphatidylinositol 4-phosphate (PtdIns(P4)), phosphatidylinositol 5-phosphate (PtdIns(P5)) and phosphatidylinositol 3,5-biphosphate (PtdIns(3,5)P2). Plays a role in protein transport between cellular compartments. Together with RAB7A facilitates endosome membrane association of the retromer cargo-selective subcomplex (CSC). May act in part as component of the SNX3-retromer complex which mediates the retrograde en [...] | Otoraplin; Belongs to the MIA/OTOR family. | 0.453 |
| Spag4 | Otor | ENSMUSP00000036484 | ENSMUSP00000028902 | Sperm-associated antigen 4 protein; Involved in spermatogenesis. Required for sperm head formation but not required to establish and maintain general polarity of the sperm head. Required for anchoring and organization of the manchette. Required for targeting of SUN3 and probably SYNE1 through a probable SUN1:SYNE3 LINC complex to the nuclear envelope and involved in accurate posterior sperm head localization of the complex. May anchor SUN3 the nuclear envelope. Involved in maintenance of the nuclear envelope integrity. May assist the organization and assembly of outer dense fibers (ODF [...] | Otoraplin; Belongs to the MIA/OTOR family. | 0.489 |
| Ucma | Otor | ENSMUSP00000110662 | ENSMUSP00000028902 | Unique cartilage matrix-associated protein C-terminal fragment; May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface. Belongs to the UCMA family. | Otoraplin; Belongs to the MIA/OTOR family. | 0.491 |
