node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Brix1 | Ebna1bp2 | ENSMUSP00000022855 | ENSMUSP00000030501 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 0.999 |
Brix1 | Mak16 | ENSMUSP00000022855 | ENSMUSP00000033983 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Protein MAK16 homolog. | 0.988 |
Brix1 | Nifk | ENSMUSP00000022855 | ENSMUSP00000027626 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.999 |
Brix1 | Nip7 | ENSMUSP00000022855 | ENSMUSP00000034392 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. | 0.997 |
Brix1 | Noc2l | ENSMUSP00000022855 | ENSMUSP00000137253 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.993 |
Brix1 | Pes1 | ENSMUSP00000022855 | ENSMUSP00000020705 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.989 |
Brix1 | Ppan | ENSMUSP00000022855 | ENSMUSP00000004203 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Suppressor of SWI4 1 homolog; May have a role in cell growth. | 0.928 |
Brix1 | Rpf1 | ENSMUSP00000022855 | ENSMUSP00000029838 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome production factor 1; May be required for ribosome biogenesis. | 0.997 |
Brix1 | Wdr12 | ENSMUSP00000022855 | ENSMUSP00000027173 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.993 |
Brix1 | Wdr74 | ENSMUSP00000022855 | ENSMUSP00000043315 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development. | 0.977 |
Ebna1bp2 | Brix1 | ENSMUSP00000030501 | ENSMUSP00000022855 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | 0.999 |
Ebna1bp2 | Mak16 | ENSMUSP00000030501 | ENSMUSP00000033983 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Protein MAK16 homolog. | 0.994 |
Ebna1bp2 | Nifk | ENSMUSP00000030501 | ENSMUSP00000027626 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.998 |
Ebna1bp2 | Nip7 | ENSMUSP00000030501 | ENSMUSP00000034392 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. | 0.996 |
Ebna1bp2 | Noc2l | ENSMUSP00000030501 | ENSMUSP00000137253 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.997 |
Ebna1bp2 | Pes1 | ENSMUSP00000030501 | ENSMUSP00000020705 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.999 |
Ebna1bp2 | Ppan | ENSMUSP00000030501 | ENSMUSP00000004203 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Suppressor of SWI4 1 homolog; May have a role in cell growth. | 0.979 |
Ebna1bp2 | Rpf1 | ENSMUSP00000030501 | ENSMUSP00000029838 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome production factor 1; May be required for ribosome biogenesis. | 0.995 |
Ebna1bp2 | Wdr12 | ENSMUSP00000030501 | ENSMUSP00000027173 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.993 |
Ebna1bp2 | Wdr74 | ENSMUSP00000030501 | ENSMUSP00000043315 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development. | 0.992 |