node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Brix1 | Ebna1bp2 | ENSMUSP00000022855 | ENSMUSP00000030501 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 0.999 |
Brix1 | Ftsj3 | ENSMUSP00000022855 | ENSMUSP00000021048 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | 0.950 |
Brix1 | Mak16 | ENSMUSP00000022855 | ENSMUSP00000033983 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Protein MAK16 homolog. | 0.988 |
Brix1 | Nifk | ENSMUSP00000022855 | ENSMUSP00000027626 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.999 |
Brix1 | Nip7 | ENSMUSP00000022855 | ENSMUSP00000034392 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. | 0.997 |
Brix1 | Noc2l | ENSMUSP00000022855 | ENSMUSP00000137253 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.993 |
Brix1 | Pes1 | ENSMUSP00000022855 | ENSMUSP00000020705 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.989 |
Brix1 | Rpf1 | ENSMUSP00000022855 | ENSMUSP00000029838 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome production factor 1; May be required for ribosome biogenesis. | 0.997 |
Brix1 | Rpf2 | ENSMUSP00000022855 | ENSMUSP00000138581 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.991 |
Brix1 | Rsl1d1 | ENSMUSP00000022855 | ENSMUSP00000113431 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. | 0.993 |
Ebna1bp2 | Brix1 | ENSMUSP00000030501 | ENSMUSP00000022855 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | 0.999 |
Ebna1bp2 | Ftsj3 | ENSMUSP00000030501 | ENSMUSP00000021048 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3; RNA 2'-O-methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. | 0.996 |
Ebna1bp2 | Mak16 | ENSMUSP00000030501 | ENSMUSP00000033983 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Protein MAK16 homolog. | 0.994 |
Ebna1bp2 | Nifk | ENSMUSP00000030501 | ENSMUSP00000027626 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.998 |
Ebna1bp2 | Nip7 | ENSMUSP00000030501 | ENSMUSP00000034392 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 60S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly. | 0.996 |
Ebna1bp2 | Noc2l | ENSMUSP00000030501 | ENSMUSP00000137253 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Nucleolar complex protein 2 homolog; Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis (By similarity). | 0.997 |
Ebna1bp2 | Pes1 | ENSMUSP00000030501 | ENSMUSP00000020705 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.999 |
Ebna1bp2 | Rpf1 | ENSMUSP00000030501 | ENSMUSP00000029838 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome production factor 1; May be required for ribosome biogenesis. | 0.995 |
Ebna1bp2 | Rpf2 | ENSMUSP00000030501 | ENSMUSP00000138581 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.996 |
Ebna1bp2 | Rsl1d1 | ENSMUSP00000030501 | ENSMUSP00000113431 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosomal L1 domain-containing protein 1; Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage. | 0.995 |