node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Abce1 | Abcf2 | ENSMUSP00000079379 | ENSMUSP00000030795 | ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'- linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway (By similarity); Belongs to the ABC transporter superfamily. ABCE family. | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | 0.969 |
Abce1 | Mrpl4 | ENSMUSP00000079379 | ENSMUSP00000003386 | ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'- linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway (By similarity); Belongs to the ABC transporter superfamily. ABCE family. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.747 |
Abce1 | Rpl11 | ENSMUSP00000079379 | ENSMUSP00000099595 | ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'- linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway (By similarity); Belongs to the ABC transporter superfamily. ABCE family. | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.639 |
Abce1 | Rpl23a | ENSMUSP00000079379 | ENSMUSP00000099541 | ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'- linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway (By similarity); Belongs to the ABC transporter superfamily. ABCE family. | 60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA (By similarity). May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination (By similarity); Belongs to the universal ribosomal protein uL23 family. | 0.689 |
Abce1 | Rps3 | ENSMUSP00000079379 | ENSMUSP00000032998 | ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'- linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway (By similarity); Belongs to the ABC transporter superfamily. ABCE family. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit (By similarity). Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (By similarity). Displays high binding affinity for 7,8-dihydro-8- oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (By similarity). Has also been shown to bind with similar affinity to intact and damaged DNA (By similarity). S [...] | 0.953 |
Abcf2 | Abce1 | ENSMUSP00000030795 | ENSMUSP00000079379 | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | ATP-binding cassette sub-family E member 1; Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'- linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway (By similarity); Belongs to the ABC transporter superfamily. ABCE family. | 0.969 |
Abcf2 | Mrpl20 | ENSMUSP00000030795 | ENSMUSP00000030942 | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | 39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family. | 0.817 |
Abcf2 | Mrpl21 | ENSMUSP00000030795 | ENSMUSP00000025745 | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | 39S ribosomal protein L21, mitochondrial. | 0.780 |
Abcf2 | Mrpl27 | ENSMUSP00000030795 | ENSMUSP00000025278 | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | 39S ribosomal protein L27, mitochondrial; Belongs to the bacterial ribosomal protein bL27 family. | 0.797 |
Abcf2 | Mrpl33 | ENSMUSP00000030795 | ENSMUSP00000031024 | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | 39S ribosomal protein L33, mitochondrial; Belongs to the bacterial ribosomal protein bL33 family. | 0.782 |
Abcf2 | Mrpl4 | ENSMUSP00000030795 | ENSMUSP00000003386 | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.817 |
Abcf2 | Rpl11 | ENSMUSP00000030795 | ENSMUSP00000099595 | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | 60S ribosomal protein L11; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.776 |
Abcf2 | Rpl23a | ENSMUSP00000030795 | ENSMUSP00000099541 | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | 60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA (By similarity). May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination (By similarity); Belongs to the universal ribosomal protein uL23 family. | 0.785 |
Abcf2 | Rps3 | ENSMUSP00000030795 | ENSMUSP00000032998 | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit (By similarity). Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (By similarity). Displays high binding affinity for 7,8-dihydro-8- oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (By similarity). Has also been shown to bind with similar affinity to intact and damaged DNA (By similarity). S [...] | 0.785 |
Abcf2 | Stip1 | ENSMUSP00000030795 | ENSMUSP00000025918 | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | Stress-induced-phosphoprotein 1; Acts as a co-chaperone for HSP90AA1. Mediates the association of the molecular chaperones HSPA8/HSC70 and HSP90. | 0.826 |
Mrpl20 | Abcf2 | ENSMUSP00000030942 | ENSMUSP00000030795 | 39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family. | ATP-binding cassette sub-family F member 2; Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily. | 0.817 |
Mrpl20 | Mrpl21 | ENSMUSP00000030942 | ENSMUSP00000025745 | 39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family. | 39S ribosomal protein L21, mitochondrial. | 0.999 |
Mrpl20 | Mrpl27 | ENSMUSP00000030942 | ENSMUSP00000025278 | 39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family. | 39S ribosomal protein L27, mitochondrial; Belongs to the bacterial ribosomal protein bL27 family. | 0.999 |
Mrpl20 | Mrpl33 | ENSMUSP00000030942 | ENSMUSP00000031024 | 39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family. | 39S ribosomal protein L33, mitochondrial; Belongs to the bacterial ribosomal protein bL33 family. | 0.999 |
Mrpl20 | Mrpl4 | ENSMUSP00000030942 | ENSMUSP00000003386 | 39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.997 |