node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
2310057J18Rik | Bpifa2 | ENSMUSP00000015663 | ENSMUSP00000046080 | Protein LEG1 homolog; May be involved in early liver development. Belongs to the LEG1 family. | BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family. | 0.634 |
2310057J18Rik | Car6 | ENSMUSP00000015663 | ENSMUSP00000030817 | Protein LEG1 homolog; May be involved in early liver development. Belongs to the LEG1 family. | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | 0.524 |
Alb | Car4 | ENSMUSP00000031314 | ENSMUSP00000099483 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | 0.413 |
Alb | Car6 | ENSMUSP00000031314 | ENSMUSP00000030817 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | 0.550 |
Alb | Cftr | ENSMUSP00000031314 | ENSMUSP00000049228 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. M [...] | 0.488 |
Alb | Serpinb7 | ENSMUSP00000031314 | ENSMUSP00000083896 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Serpin B7; Might function as an inhibitor of Lys-specific proteases. Might influence the maturation of megakaryocytes via its action as a serpin (By similarity); Belongs to the serpin family. Ov-serpin subfamily. | 0.916 |
Bpifa2 | 2310057J18Rik | ENSMUSP00000046080 | ENSMUSP00000015663 | BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family. | Protein LEG1 homolog; May be involved in early liver development. Belongs to the LEG1 family. | 0.634 |
Bpifa2 | Car6 | ENSMUSP00000046080 | ENSMUSP00000030817 | BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family. | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | 0.814 |
Bpifa2 | Mucl2 | ENSMUSP00000046080 | ENSMUSP00000044814 | BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family. | Mucin-like protein 2. | 0.894 |
Car4 | Alb | ENSMUSP00000099483 | ENSMUSP00000031314 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.413 |
Car4 | Car6 | ENSMUSP00000099483 | ENSMUSP00000030817 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | 0.570 |
Car4 | Rpf2 | ENSMUSP00000099483 | ENSMUSP00000138581 | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.568 |
Car6 | 2310057J18Rik | ENSMUSP00000030817 | ENSMUSP00000015663 | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | Protein LEG1 homolog; May be involved in early liver development. Belongs to the LEG1 family. | 0.524 |
Car6 | Alb | ENSMUSP00000030817 | ENSMUSP00000031314 | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.550 |
Car6 | Bpifa2 | ENSMUSP00000030817 | ENSMUSP00000046080 | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family. | 0.814 |
Car6 | Car4 | ENSMUSP00000030817 | ENSMUSP00000099483 | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | 0.570 |
Car6 | Cftr | ENSMUSP00000030817 | ENSMUSP00000049228 | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. M [...] | 0.551 |
Car6 | Chst8 | ENSMUSP00000030817 | ENSMUSP00000159050 | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | Carbohydrate sulfotransferase 8; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Only active against terminal GalNAcbeta1,GalNAcbeta. Not active toward chondroitin. | 0.508 |
Car6 | Chst9 | ENSMUSP00000030817 | ENSMUSP00000049975 | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | Carbohydrate sulfotransferase 9; Catalyzes the transfer of sulfate to position 4 of non- reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. Participates in biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulfation of their carbohydrate structures. Has a higher activity toward carbonic anhydrase VI than toward lutropin. Only active against terminal GalNAcbeta1,GalNAcbeta. | 0.539 |
Car6 | Mucl2 | ENSMUSP00000030817 | ENSMUSP00000044814 | Carbonic anhydrase 6; Reversible hydration of carbon dioxide. Its role in saliva is unknown. | Mucin-like protein 2. | 0.785 |