node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adam3 | Man2b2 | ENSMUSP00000033958 | ENSMUSP00000031002 | A disintegrin and metallopeptidase domain 3; Involved in fertilization by controlling sperm migration into oviduct. | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | 0.612 |
Adam3 | Ropn1l | ENSMUSP00000033958 | ENSMUSP00000106038 | A disintegrin and metallopeptidase domain 3; Involved in fertilization by controlling sperm migration into oviduct. | Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. | 0.553 |
Adam3 | Spaca1 | ENSMUSP00000033958 | ENSMUSP00000029927 | A disintegrin and metallopeptidase domain 3; Involved in fertilization by controlling sperm migration into oviduct. | Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility. | 0.515 |
Adam3 | Spag17 | ENSMUSP00000033958 | ENSMUSP00000134066 | A disintegrin and metallopeptidase domain 3; Involved in fertilization by controlling sperm migration into oviduct. | Sperm-associated antigen 17; Component of the central pair apparatus of ciliary axonemes. Plays a critical role in the function and structure of motile cilia. May play a role in endochondral bone formation, most likely because of a function in primary cilia of chondrocytes and osteoblasts. | 0.560 |
Adam3 | Zan | ENSMUSP00000033958 | ENSMUSP00000114068 | A disintegrin and metallopeptidase domain 3; Involved in fertilization by controlling sperm migration into oviduct. | Zonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling. | 0.579 |
Adam3 | Zp3r | ENSMUSP00000033958 | ENSMUSP00000045443 | A disintegrin and metallopeptidase domain 3; Involved in fertilization by controlling sperm migration into oviduct. | Zona pellucida sperm-binding protein 3 receptor; Binds to ZP3 glycoprotein in egg zona pellucida. Probably involved in interactions between sperm acrosome and egg zona pellucida during and immediately following the acrosome reaction. | 0.829 |
Adam3 | Zpbp2 | ENSMUSP00000033958 | ENSMUSP00000017339 | A disintegrin and metallopeptidase domain 3; Involved in fertilization by controlling sperm migration into oviduct. | Zona pellucida-binding protein 2; Is implicated in sperm-oocyte interaction during fertilization. | 0.713 |
Man2b1 | Man2b2 | ENSMUSP00000034121 | ENSMUSP00000031002 | Lysosomal alpha-mannosidase; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | 0.923 |
Man2b1 | Man2c1 | ENSMUSP00000034121 | ENSMUSP00000125478 | Lysosomal alpha-mannosidase; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. | Alpha-mannosidase 2C1; Cleaves alpha 1,2-, alpha 1,3-, and alpha 1,6-linked mannose residues from glycoproteins. Involved in the degradation of free oligosaccharides in the cytoplasm. | 0.970 |
Man2b1 | Naga | ENSMUSP00000034121 | ENSMUSP00000023088 | Lysosomal alpha-mannosidase; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. | Alpha-N-acetylgalactosaminidase; Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids (By similarity); Belongs to the glycosyl hydrolase 27 family. | 0.596 |
Man2b2 | Adam3 | ENSMUSP00000031002 | ENSMUSP00000033958 | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | A disintegrin and metallopeptidase domain 3; Involved in fertilization by controlling sperm migration into oviduct. | 0.612 |
Man2b2 | Man2b1 | ENSMUSP00000031002 | ENSMUSP00000034121 | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | Lysosomal alpha-mannosidase; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. | 0.923 |
Man2b2 | Man2c1 | ENSMUSP00000031002 | ENSMUSP00000125478 | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | Alpha-mannosidase 2C1; Cleaves alpha 1,2-, alpha 1,3-, and alpha 1,6-linked mannose residues from glycoproteins. Involved in the degradation of free oligosaccharides in the cytoplasm. | 0.933 |
Man2b2 | Naga | ENSMUSP00000031002 | ENSMUSP00000023088 | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | Alpha-N-acetylgalactosaminidase; Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids (By similarity); Belongs to the glycosyl hydrolase 27 family. | 0.595 |
Man2b2 | Ropn1l | ENSMUSP00000031002 | ENSMUSP00000106038 | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. | 0.582 |
Man2b2 | Spaca1 | ENSMUSP00000031002 | ENSMUSP00000029927 | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis. Important for male fertility. | 0.567 |
Man2b2 | Spag17 | ENSMUSP00000031002 | ENSMUSP00000134066 | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | Sperm-associated antigen 17; Component of the central pair apparatus of ciliary axonemes. Plays a critical role in the function and structure of motile cilia. May play a role in endochondral bone formation, most likely because of a function in primary cilia of chondrocytes and osteoblasts. | 0.561 |
Man2b2 | Zan | ENSMUSP00000031002 | ENSMUSP00000114068 | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | Zonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling. | 0.573 |
Man2b2 | Zp3r | ENSMUSP00000031002 | ENSMUSP00000045443 | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | Zona pellucida sperm-binding protein 3 receptor; Binds to ZP3 glycoprotein in egg zona pellucida. Probably involved in interactions between sperm acrosome and egg zona pellucida during and immediately following the acrosome reaction. | 0.644 |
Man2b2 | Zpbp2 | ENSMUSP00000031002 | ENSMUSP00000017339 | Epididymis-specific alpha-mannosidase; Plays an important role in the early step of spermatogenesis; Belongs to the glycosyl hydrolase 38 family. | Zona pellucida-binding protein 2; Is implicated in sperm-oocyte interaction during fertilization. | 0.641 |