node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ap4m1 | D6Wsu163e | ENSMUSP00000019662 | ENSMUSP00000032497 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and [...] | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | 0.443 |
Ap4m1 | Exoc8 | ENSMUSP00000019662 | ENSMUSP00000095915 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and [...] | Exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | 0.499 |
Ap4m1 | Tmem87a | ENSMUSP00000019662 | ENSMUSP00000087500 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and [...] | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN). | 0.540 |
D6Wsu163e | Ap4m1 | ENSMUSP00000032497 | ENSMUSP00000019662 | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and [...] | 0.443 |
D6Wsu163e | Exoc8 | ENSMUSP00000032497 | ENSMUSP00000095915 | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | Exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | 0.809 |
D6Wsu163e | Minar2 | ENSMUSP00000032497 | ENSMUSP00000125952 | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | Major intrinsically disordered NOTCH2-binding receptor 1-like homolog; Belongs to the MINAR family. | 0.671 |
D6Wsu163e | Ppp1r21 | ENSMUSP00000032497 | ENSMUSP00000048443 | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | Protein phosphatase 1 regulatory subunit 21; utative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. | 0.843 |
D6Wsu163e | Slx1b | ENSMUSP00000032497 | ENSMUSP00000118182 | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.813 |
D6Wsu163e | Tbck | ENSMUSP00000032497 | ENSMUSP00000129205 | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | TBC domain-containing protein kinase-like protein; Involved in the modulation of mTOR signaling and expression of mTOR complex components. Involved in the regulation of cell proliferation and growth. Involved in the control of actin-cytoskeleton organization; Belongs to the protein kinase superfamily. | 0.776 |
D6Wsu163e | Tmem106c | ENSMUSP00000032497 | ENSMUSP00000069764 | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | Transmembrane protein 106C. | 0.447 |
D6Wsu163e | Tmem87a | ENSMUSP00000032497 | ENSMUSP00000087500 | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN). | 0.447 |
D6Wsu163e | Zfp330 | ENSMUSP00000032497 | ENSMUSP00000034147 | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | Zinc finger protein 330; Belongs to the NOA36 family. | 0.543 |
D6Wsu163e | Zfp719 | ENSMUSP00000032497 | ENSMUSP00000050968 | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | Zinc finger protein 719. | 0.645 |
Exoc8 | Ap4m1 | ENSMUSP00000095915 | ENSMUSP00000019662 | Exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system (By similarity). It is also involved in protein sorting to the basolateral membrane in epithelial cells and [...] | 0.499 |
Exoc8 | D6Wsu163e | ENSMUSP00000095915 | ENSMUSP00000032497 | Exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | 0.809 |
Exoc8 | Slx1b | ENSMUSP00000095915 | ENSMUSP00000118182 | Exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.744 |
Exoc8 | Tmem87a | ENSMUSP00000095915 | ENSMUSP00000087500 | Exocyst complex component 8; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN). | 0.565 |
Minar2 | D6Wsu163e | ENSMUSP00000125952 | ENSMUSP00000032497 | Major intrinsically disordered NOTCH2-binding receptor 1-like homolog; Belongs to the MINAR family. | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | 0.671 |
Minar2 | Zfp719 | ENSMUSP00000125952 | ENSMUSP00000050968 | Major intrinsically disordered NOTCH2-binding receptor 1-like homolog; Belongs to the MINAR family. | Zinc finger protein 719. | 0.766 |
Ppp1r21 | D6Wsu163e | ENSMUSP00000048443 | ENSMUSP00000032497 | Protein phosphatase 1 regulatory subunit 21; utative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. | Protein C12orf4 homolog; Plays a role in mast cell degranulation. | 0.843 |