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Gsr protein (mouse) - STRING interaction network
"Gsr" - Glutathione reductase, mitochondrial in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
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[Homology]
Score
GsrGlutathione reductase, mitochondrial; Maintains high levels of reduced glutathione in the cytosol (500 aa)    
Predicted Functional Partners:
Gpx1
Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown (201 aa)
   
 
  0.986
Gpx4
Phospholipid hydroperoxide glutathione peroxidase, nuclear; Could play a major role in protecting mammals from the toxicity of ingested lipid hydroperoxides. Essential for embryonic development. Protects from radiation and oxidative damage. Stabilizes the condensed chromatin in sperm nuclei and is necessary for male fertility (253 aa)
   
 
  0.986
Gpx2
Glutathione peroxidase 2 (190 aa)
   
 
  0.985
Gpx7
Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks (By similarity) (186 aa)
   
 
  0.982
Gpx3
Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione (226 aa)
   
 
  0.981
Gss
Glutathione synthetase; Belongs to the eukaryotic GSH synthase family (474 aa)
     
 
  0.981
Cat
Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family (527 aa)
     
 
  0.981
Gpx8
Glutathione peroxidase 8 (putative); Belongs to the glutathione peroxidase family (209 aa)
   
 
  0.977
Gpx6
Glutathione peroxidase 6; Belongs to the glutathione peroxidase family (221 aa)
   
 
  0.975
Gpx5
Epididymal secretory glutathione peroxidase; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. May constitute a glutathione peroxidase-like protective system against peroxide damage in sperm membrane lipids (237 aa)
   
 
  0.972
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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