STRINGSTRING
Ces1c protein (mouse) - STRING interaction network
"Ces1c" - Carboxylesterase 1C in Mus musculus
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Ces1cCarboxylesterase 1C; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant; Belongs to the type-B carboxylesterase/lipase family (554 aa)    
Predicted Functional Partners:
Cyp2e1
Cytochrome P450 2E1; Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites (493 aa)
     
 
  0.916
Mpo
Myeloperoxidase; Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity; Belongs to the peroxidase family. XPO subfamily (718 aa)
       
  0.902
Ugt2b1
UDP-glucuronosyltransferase; UDP glucuronosyltransferase 2 family, polypeptide B1; Belongs to the UDP-glycosyltransferase family (529 aa)
     
 
  0.865
Ugt2b5
UDP-glucuronosyltransferase 2B17; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (530 aa)
     
 
  0.863
Ugt2a3
UDP-glucuronosyltransferase 2A3; UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity); Belongs to the UDP-glycosyltransferase family (534 aa)
     
 
  0.815
Ugt2b36
UDP-glucuronosyltransferase; UDP glucuronosyltransferase 2 family, polypeptide B36; Belongs to the UDP-glycosyltransferase family (530 aa)
     
 
  0.793
Rdh7
Retinol dehydrogenase 7; Acts on androgens and retinols, i.e. has steroid 3- alpha- and 17-beta-dehydrogenase and cis/trans-retinol catalytic activities (316 aa)
     
   
  0.741
Ugt2b34
UDP-glucuronosyltransferase; UDP glucuronosyltransferase 2 family, polypeptide B34; Belongs to the UDP-glycosyltransferase family (532 aa)
     
 
  0.741
Ugt1a1
UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (535 aa)
     
 
  0.734
Gusb
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates (648 aa)
     
  0.729
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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