STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Acrv1Acrosomal protein SP-10. (261 aa)    
Predicted Functional Partners:
4930519G04Rik
RIKEN cDNA 4930519G04 gene.
   
    0.768
Mbd3l2
Methyl-CpG-binding domain protein 3-like 2.
   
  
 0.762
1700016D06Rik
RIKEN cDNA 1700016D06 gene.
   
    0.740
Sp9
Transcription factor Sp9; Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos.
    
 
 0.691
Tnp1
Spermatid nuclear transition protein 1; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. The histone H2AB1-H2BC1/TH2B dimer is required for loading of TNP1 onto chromatin.
   
  
 0.650
Pate7
Prostate and testis-expressed 7.
      
 0.618
Pate11
Secreted TFP/Ly-6/uPAR protein PATE-P.
      
 0.608
Pate3
Prostate and testis expressed protein 3.
      
 0.601
Akap4
A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility.
   
  
 0.598
Zpbp
Zona pellucida-binding protein 1; Plays a role in acrosome compaction and sperm morphogenesis. Is implicated in sperm-oocyte interaction during fertilization. Belongs to the zona pellucida-binding protein Sp38 family.
   
  
 0.587
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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