node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
2610028H24Rik | Akip1 | ENSMUSP00000090061 | ENSMUSP00000033335 | RIKEN cDNA 2610028H24 gene. | A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity). | 0.491 |
2610028H24Rik | C2cd2 | ENSMUSP00000090061 | ENSMUSP00000127368 | RIKEN cDNA 2610028H24 gene. | C2 domain-containing protein 2. | 0.515 |
2610028H24Rik | Lca5 | ENSMUSP00000090061 | ENSMUSP00000034791 | RIKEN cDNA 2610028H24 gene. | Lebercilin; Involved in intraflagellar protein (IFT) transport in photoreceptor cilia. | 0.650 |
2610028H24Rik | Tspear | ENSMUSP00000090061 | ENSMUSP00000090020 | RIKEN cDNA 2610028H24 gene. | Thrombospondin-type laminin G domain and EAR repeat-containing protein; Plays a critical role in tooth and hair follicle morphogenesis through regulation of the Notch signaling pathway. May play a role in development or function of the auditory system. | 0.552 |
2610028H24Rik | Ybey | ENSMUSP00000090061 | ENSMUSP00000045647 | RIKEN cDNA 2610028H24 gene. | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation; Belongs to the endoribonuclease YbeY family. | 0.607 |
Akip1 | 2610028H24Rik | ENSMUSP00000033335 | ENSMUSP00000090061 | A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity). | RIKEN cDNA 2610028H24 gene. | 0.491 |
Akip1 | C2cd2 | ENSMUSP00000033335 | ENSMUSP00000127368 | A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity). | C2 domain-containing protein 2. | 0.641 |
Akip1 | Erg28 | ENSMUSP00000033335 | ENSMUSP00000021676 | A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity). | Ergosterol biosynthetic protein 28 homolog. | 0.490 |
Akip1 | Lca5 | ENSMUSP00000033335 | ENSMUSP00000034791 | A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity). | Lebercilin; Involved in intraflagellar protein (IFT) transport in photoreceptor cilia. | 0.647 |
Akip1 | Prdm15 | ENSMUSP00000033335 | ENSMUSP00000093533 | A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity). | PR domain zinc finger protein 15; Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in th [...] | 0.495 |
Akip1 | Ybey | ENSMUSP00000033335 | ENSMUSP00000045647 | A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity). | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation; Belongs to the endoribonuclease YbeY family. | 0.646 |
C2cd2 | 2610028H24Rik | ENSMUSP00000127368 | ENSMUSP00000090061 | C2 domain-containing protein 2. | RIKEN cDNA 2610028H24 gene. | 0.515 |
C2cd2 | Akip1 | ENSMUSP00000127368 | ENSMUSP00000033335 | C2 domain-containing protein 2. | A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity). | 0.641 |
C2cd2 | Erg28 | ENSMUSP00000127368 | ENSMUSP00000021676 | C2 domain-containing protein 2. | Ergosterol biosynthetic protein 28 homolog. | 0.410 |
C2cd2 | Lca5 | ENSMUSP00000127368 | ENSMUSP00000034791 | C2 domain-containing protein 2. | Lebercilin; Involved in intraflagellar protein (IFT) transport in photoreceptor cilia. | 0.653 |
C2cd2 | Prdm15 | ENSMUSP00000127368 | ENSMUSP00000093533 | C2 domain-containing protein 2. | PR domain zinc finger protein 15; Sequence-specific DNA-binding transcriptional regulator. Plays a role as a molecular node in a transcriptional network regulating embryonic development and cell fate decision. Stimulates the expression of upstream key transcriptional activators and repressors of the Wnt/beta-catenin and MAPK/ERK pathways, respectively, that are essential for naive pluripotency and self-renewal maintenance of embryonic stem cells (ESCs). Specifically promotes SPRY1 and RSPO1 transcription activation through recognition and direct binding of a specific DNA sequence in th [...] | 0.712 |
C2cd2 | Tspear | ENSMUSP00000127368 | ENSMUSP00000090020 | C2 domain-containing protein 2. | Thrombospondin-type laminin G domain and EAR repeat-containing protein; Plays a critical role in tooth and hair follicle morphogenesis through regulation of the Notch signaling pathway. May play a role in development or function of the auditory system. | 0.726 |
C2cd2 | Ybey | ENSMUSP00000127368 | ENSMUSP00000045647 | C2 domain-containing protein 2. | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation; Belongs to the endoribonuclease YbeY family. | 0.612 |
Ddx58 | Lca5 | ENSMUSP00000042433 | ENSMUSP00000034791 | Antiviral innate immune response receptor RIG-I; Innate immune receptor that senses cytoplasmic viral nucleic acids and activates a downstream signaling cascade leading to the production of type I interferons and proinflammatory cytokines. Forms a ribonucleoprotein complex with viral RNAs on which it homooligomerizes to form filaments. The homooligomerization allows the recruitment of RNF135 an E3 ubiquitin-protein ligase that activates and amplifies the RIG-I-mediated antiviral signaling in an RNA length-dependent manner through ubiquitination-dependent and -independent mechanisms. Up [...] | Lebercilin; Involved in intraflagellar protein (IFT) transport in photoreceptor cilia. | 0.606 |
Erg28 | Akip1 | ENSMUSP00000021676 | ENSMUSP00000033335 | Ergosterol biosynthetic protein 28 homolog. | A-kinase-interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (By similarity). | 0.490 |