STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Btbd16BTB/POZ domain-containing protein 16. (522 aa)    
Predicted Functional Partners:
Ttc34
Tetratricopeptide repeat protein 34.
   
  
 0.603
Catsperg1
Cation channel sperm-associated protein subunit gamma 1; Belongs to the CATSPERG family.
   
  
 0.555
Mblac1
Metallo-beta-lactamase domain-containing protein 1.
      
 0.555
Catsperg2
Cation channel sperm-associated protein subunit gamma 2; Probably involved in sperm cell hyperactivation via its association with CATSPER1. Sperm cell hyperactivation is needed for sperm motility which is essential late in the preparation of sperm for fertilization.
   
  
 0.529
Ccdc116
Coiled-coil domain-containing protein 116.
   
  
 0.502
Actrt2
Actin-related protein T2.
   
  
 0.480
Ydjc
Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.
      
 0.478
Prkcq
Protein kinase C theta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that mediates non-redundant functions in T-cell receptor (TCR) signaling, including T-cells activation, proliferation, differentiation and survival, by mediating activation of multiple transcription factors such as NF-kappa-B, JUN, NFATC1 and NFATC2. In TCR-CD3/CD28-co-stimulated T-cells, is required for the activation of NF-kappa-B and JUN, which in turn are essential for IL2 production, and participates in the calcium-dependent NFATC1 and NFATC2 transact [...]
   
  
 0.470
Cdx4
Homeobox protein CDX-4.
      
 0.468
Cdr2l
Cerebellar degeneration-related protein 2-like; Belongs to the CDR2 family.
      
 0.463
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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