node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
2210010C04Rik | Cel | ENSMUSP00000031931 | ENSMUSP00000028161 | RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family. | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). | 0.978 |
2210010C04Rik | Cela2a | ENSMUSP00000031931 | ENSMUSP00000099539 | RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family. | Chymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. | 0.838 |
2210010C04Rik | Cpa2 | ENSMUSP00000031931 | ENSMUSP00000093771 | RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family. | Carboxypeptidase A2. | 0.801 |
2210010C04Rik | Cuzd1 | ENSMUSP00000031931 | ENSMUSP00000037168 | RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family. | CUB and zona pellucida-like domain-containing protein 1; CUZD1 antiserum inhibits cell attachment and proliferation of ovarian cancer cells so may be involved in these processes (By similarity). May also play a role in the uterus during late pregnancy and/or in trypsin activation in pancreatic acinar cells. | 0.612 |
2210010C04Rik | Gp2 | ENSMUSP00000031931 | ENSMUSP00000033255 | RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family. | Pancreatic secretory granule membrane major glycoprotein GP2. | 0.545 |
2210010C04Rik | Prss2 | ENSMUSP00000031931 | ENSMUSP00000065393 | RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family. | Anionic trypsin-2. | 0.967 |
2210010C04Rik | Serpini2 | ENSMUSP00000031931 | ENSMUSP00000046943 | RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family. | Serpin I2; Belongs to the serpin family. | 0.689 |
2210010C04Rik | Sycn | ENSMUSP00000031931 | ENSMUSP00000112770 | RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family. | Syncollin; Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues. | 0.762 |
Cel | 2210010C04Rik | ENSMUSP00000028161 | ENSMUSP00000031931 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). | RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family. | 0.978 |
Cel | Cela2a | ENSMUSP00000028161 | ENSMUSP00000099539 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). | Chymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. | 0.968 |
Cel | Cpa2 | ENSMUSP00000028161 | ENSMUSP00000093771 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). | Carboxypeptidase A2. | 0.728 |
Cel | Cuzd1 | ENSMUSP00000028161 | ENSMUSP00000037168 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). | CUB and zona pellucida-like domain-containing protein 1; CUZD1 antiserum inhibits cell attachment and proliferation of ovarian cancer cells so may be involved in these processes (By similarity). May also play a role in the uterus during late pregnancy and/or in trypsin activation in pancreatic acinar cells. | 0.588 |
Cel | Gp2 | ENSMUSP00000028161 | ENSMUSP00000033255 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). | Pancreatic secretory granule membrane major glycoprotein GP2. | 0.653 |
Cel | Prss2 | ENSMUSP00000028161 | ENSMUSP00000065393 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). | Anionic trypsin-2. | 0.972 |
Cel | Serpini2 | ENSMUSP00000028161 | ENSMUSP00000046943 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). | Serpin I2; Belongs to the serpin family. | 0.590 |
Cel | Sycn | ENSMUSP00000028161 | ENSMUSP00000112770 | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). | Syncollin; Functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. May have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues. | 0.766 |
Cela2a | 2210010C04Rik | ENSMUSP00000099539 | ENSMUSP00000031931 | Chymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. | RIKEN cDNA 2210010C04 gene; Belongs to the peptidase S1 family. | 0.838 |
Cela2a | Cel | ENSMUSP00000099539 | ENSMUSP00000028161 | Chymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. | Bile salt-activated lipase; Catalyzes the hydrolysis of a wide range of substrates including cholesteryl esters, phospholipids, lysophospholipids, di- and tri-acylglycerols, and fatty acid esters of hydroxy fatty acids (FAHFAs). Preferentially hydrolyzes FAHFAs with the ester bond further away from the carboxylate. Unsaturated FAHFAs are hydrolyzed more quickly than saturated FAHFAs. Has an essential role in the complete digestion of dietary lipids and their intestinal absorption, along with the absorption of fat-soluble vitamins (By similarity). | 0.968 |
Cela2a | Cpa2 | ENSMUSP00000099539 | ENSMUSP00000093771 | Chymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. | Carboxypeptidase A2. | 0.895 |
Cela2a | Cuzd1 | ENSMUSP00000099539 | ENSMUSP00000037168 | Chymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily. | CUB and zona pellucida-like domain-containing protein 1; CUZD1 antiserum inhibits cell attachment and proliferation of ovarian cancer cells so may be involved in these processes (By similarity). May also play a role in the uterus during late pregnancy and/or in trypsin activation in pancreatic acinar cells. | 0.560 |