node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adh1 | Aldh3b2 | ENSMUSP00000004232 | ENSMUSP00000115356 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family. | 0.927 |
Adh1 | Cyp2e1 | ENSMUSP00000004232 | ENSMUSP00000026552 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | 0.979 |
Adh1 | Fmo1 | ENSMUSP00000004232 | ENSMUSP00000037259 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Dimethylaniline monooxygenase [N-oxide-forming] 1; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. | 0.443 |
Adh1 | Inmt | ENSMUSP00000004232 | ENSMUSP00000003569 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Indolethylamine N-methyltransferase; Catalyzes the N-methylation of tryptamine and structurally related compounds (By similarity). Functions as thioether S- methyltransferase and is active with a variety of thioethers and the corresponding selenium and tellurium compounds, including 3- methylthiopropionaldehyde, dimethyl selenide, dimethyl telluride, 2- methylthioethylamine, 2-methylthioethanol, methyl-n-propyl sulfide and diethyl sulfide. Plays an important role in the detoxification of selenium compounds; Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNM [...] | 0.483 |
Adh1 | Maob | ENSMUSP00000004232 | ENSMUSP00000040550 | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity). | 0.935 |
Aldh3b2 | Adh1 | ENSMUSP00000115356 | ENSMUSP00000004232 | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family. | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | 0.927 |
Aldh3b2 | Cyp2e1 | ENSMUSP00000115356 | ENSMUSP00000026552 | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family. | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | 0.913 |
Aldh3b2 | Fmo1 | ENSMUSP00000115356 | ENSMUSP00000037259 | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family. | Dimethylaniline monooxygenase [N-oxide-forming] 1; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. | 0.415 |
Aldh3b2 | Maob | ENSMUSP00000115356 | ENSMUSP00000040550 | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity). | 0.926 |
B4galt4 | Cdc40 | ENSMUSP00000023482 | ENSMUSP00000044305 | Beta-1,4-galactosyltransferase 4; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | 0.515 |
B4galt4 | Fmo1 | ENSMUSP00000023482 | ENSMUSP00000037259 | Beta-1,4-galactosyltransferase 4; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | Dimethylaniline monooxygenase [N-oxide-forming] 1; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. | 0.484 |
B4galt4 | Hmg20b | ENSMUSP00000023482 | ENSMUSP00000020454 | Beta-1,4-galactosyltransferase 4; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | High mobility group 20B; Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters (By similarity). | 0.465 |
Cdc40 | B4galt4 | ENSMUSP00000044305 | ENSMUSP00000023482 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | Beta-1,4-galactosyltransferase 4; Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids; Belongs to the glycosyltransferase 7 family. | 0.515 |
Cdc40 | Fmo1 | ENSMUSP00000044305 | ENSMUSP00000037259 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | Dimethylaniline monooxygenase [N-oxide-forming] 1; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. | 0.488 |
Cdc40 | Hmg20b | ENSMUSP00000044305 | ENSMUSP00000020454 | Pre-mRNA-processing factor 17; Required for pre-mRNA splicing as component of the activated spliceosome. | High mobility group 20B; Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters (By similarity). | 0.469 |
Cdo1 | Cyp2e1 | ENSMUSP00000046517 | ENSMUSP00000026552 | Cysteine dioxygenase type 1; Belongs to the cysteine dioxygenase family. | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | 0.596 |
Cdo1 | Fmo1 | ENSMUSP00000046517 | ENSMUSP00000037259 | Cysteine dioxygenase type 1; Belongs to the cysteine dioxygenase family. | Dimethylaniline monooxygenase [N-oxide-forming] 1; This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. Form I catalyzes the N-oxygenation of secondary and tertiary amines. | 0.452 |
Cyp2e1 | Adh1 | ENSMUSP00000026552 | ENSMUSP00000004232 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Alcohol dehydrogenase 1; Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily. | 0.979 |
Cyp2e1 | Aldh3b2 | ENSMUSP00000026552 | ENSMUSP00000115356 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Aldehyde dehydrogenase family 3 member B2; Oxidizes medium and long chain aldehydes into non-toxic fatty acids; Belongs to the aldehyde dehydrogenase family. | 0.913 |
Cyp2e1 | Cdo1 | ENSMUSP00000026552 | ENSMUSP00000046517 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Cysteine dioxygenase type 1; Belongs to the cysteine dioxygenase family. | 0.596 |