node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Abca7 | Abi3 | ENSMUSP00000128121 | ENSMUSP00000061893 | ATP-binding cassette sub-family A member 7; Probable ATP-binding cassette (ABC) transporter that plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux (By similarity). May regulate cellular ceramide homeostasis during keratinocyte differentiation (By similarity). Involved in lipid raft organization and CD1D localization on thymocytes and antigen-presenting cells, which plays an important role in natural killer T-cell development and activation. P [...] | ABI gene family member 3; Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility; Belongs to the ABI family. | 0.527 |
Abca7 | Cass4 | ENSMUSP00000128121 | ENSMUSP00000104764 | ATP-binding cassette sub-family A member 7; Probable ATP-binding cassette (ABC) transporter that plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux (By similarity). May regulate cellular ceramide homeostasis during keratinocyte differentiation (By similarity). Involved in lipid raft organization and CD1D localization on thymocytes and antigen-presenting cells, which plays an important role in natural killer T-cell development and activation. P [...] | Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity). | 0.724 |
Abca7 | Echdc3 | ENSMUSP00000128121 | ENSMUSP00000037371 | ATP-binding cassette sub-family A member 7; Probable ATP-binding cassette (ABC) transporter that plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux (By similarity). May regulate cellular ceramide homeostasis during keratinocyte differentiation (By similarity). Involved in lipid raft organization and CD1D localization on thymocytes and antigen-presenting cells, which plays an important role in natural killer T-cell development and activation. P [...] | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.457 |
Abca7 | Nme8 | ENSMUSP00000128121 | ENSMUSP00000089358 | ATP-binding cassette sub-family A member 7; Probable ATP-binding cassette (ABC) transporter that plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux (By similarity). May regulate cellular ceramide homeostasis during keratinocyte differentiation (By similarity). Involved in lipid raft organization and CD1D localization on thymocytes and antigen-presenting cells, which plays an important role in natural killer T-cell development and activation. P [...] | Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds (By similarity). | 0.711 |
Abi3 | Abca7 | ENSMUSP00000061893 | ENSMUSP00000128121 | ABI gene family member 3; Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility; Belongs to the ABI family. | ATP-binding cassette sub-family A member 7; Probable ATP-binding cassette (ABC) transporter that plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux (By similarity). May regulate cellular ceramide homeostasis during keratinocyte differentiation (By similarity). Involved in lipid raft organization and CD1D localization on thymocytes and antigen-presenting cells, which plays an important role in natural killer T-cell development and activation. P [...] | 0.527 |
Abi3 | Cass4 | ENSMUSP00000061893 | ENSMUSP00000104764 | ABI gene family member 3; Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility; Belongs to the ABI family. | Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity). | 0.437 |
Abi3 | Echdc3 | ENSMUSP00000061893 | ENSMUSP00000037371 | ABI gene family member 3; Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility; Belongs to the ABI family. | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.472 |
Abi3 | Scimp | ENSMUSP00000061893 | ENSMUSP00000104174 | ABI gene family member 3; Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility; Belongs to the ABI family. | SLP adapter and CSK-interacting membrane protein; Lipid tetraspanin-associated transmembrane adapter/mediator that acts as a scaffold for Src-family kinases and other signaling proteins in immune cells. It is involved in major histocompatibility complex class II (MHC-II) signaling transduction in B cells, where it is required in generating the calcium response and enhancing ERK activity upon MHC-II stimulation (By similarity). In dendritic cells, it is involved in sustaining CLEC7A/DECTIN1 signaling after CLEC7A activation by fungal beta-glucans. It also acts as an agonist- inducible s [...] | 0.407 |
Cass4 | Abca7 | ENSMUSP00000104764 | ENSMUSP00000128121 | Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity). | ATP-binding cassette sub-family A member 7; Probable ATP-binding cassette (ABC) transporter that plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux (By similarity). May regulate cellular ceramide homeostasis during keratinocyte differentiation (By similarity). Involved in lipid raft organization and CD1D localization on thymocytes and antigen-presenting cells, which plays an important role in natural killer T-cell development and activation. P [...] | 0.724 |
Cass4 | Abi3 | ENSMUSP00000104764 | ENSMUSP00000061893 | Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity). | ABI gene family member 3; Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility; Belongs to the ABI family. | 0.437 |
Cass4 | Echdc3 | ENSMUSP00000104764 | ENSMUSP00000037371 | Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity). | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.507 |
Cass4 | Nme8 | ENSMUSP00000104764 | ENSMUSP00000089358 | Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity). | Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds (By similarity). | 0.843 |
Cutal | Echdc3 | ENSMUSP00000108691 | ENSMUSP00000037371 | CutA divalent cation tolerance homolog-like. | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.502 |
Echdc3 | Abca7 | ENSMUSP00000037371 | ENSMUSP00000128121 | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | ATP-binding cassette sub-family A member 7; Probable ATP-binding cassette (ABC) transporter that plays a role in lipid homeostasis and macrophage-mediated phagocytosis. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux (By similarity). May regulate cellular ceramide homeostasis during keratinocyte differentiation (By similarity). Involved in lipid raft organization and CD1D localization on thymocytes and antigen-presenting cells, which plays an important role in natural killer T-cell development and activation. P [...] | 0.457 |
Echdc3 | Abi3 | ENSMUSP00000037371 | ENSMUSP00000061893 | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | ABI gene family member 3; Inhibits ectopic tumor cell metastasis of SRD cells. In vitro, reduces cell motility; Belongs to the ABI family. | 0.472 |
Echdc3 | Cass4 | ENSMUSP00000037371 | ENSMUSP00000104764 | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | Cas scaffolding protein family member 4; Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading (By similarity). | 0.507 |
Echdc3 | Cutal | ENSMUSP00000037371 | ENSMUSP00000108691 | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | CutA divalent cation tolerance homolog-like. | 0.502 |
Echdc3 | Ivd | ENSMUSP00000037371 | ENSMUSP00000028807 | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | Isovaleryl-CoA dehydrogenase, mitochondrial; Belongs to the acyl-CoA dehydrogenase family. | 0.483 |
Echdc3 | Nme8 | ENSMUSP00000037371 | ENSMUSP00000089358 | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | Thioredoxin domain-containing protein 3; Probably required during the final stages of sperm tail maturation in the testis and/or epididymis, where extensive disulfide bonding of fibrous sheath (FS) proteins occurs. May be involved in the reduction of disulfide bonds within the sperm FS components. In vitro, it has neither NDP kinase nor reducing activity on disulfide bonds (By similarity). | 0.504 |
Echdc3 | Proser2 | ENSMUSP00000037371 | ENSMUSP00000110592 | Enoyl-CoA hydratase domain-containing protein 3, mitochondrial; May play a role in fatty acid biosynthesis and insulin sensitivity; Belongs to the enoyl-CoA hydratase/isomerase family. | Proline and serine-rich protein 2. | 0.477 |