| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Aadac | Apob | ENSMUSP00000029325 | ENSMUSP00000036044 | Arylacetamide deacetylase; Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly (By similarity). Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. | Apolipoprotein B-100; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | 0.487 |
| Aadac | Ces1e | ENSMUSP00000029325 | ENSMUSP00000034173 | Arylacetamide deacetylase; Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly (By similarity). Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. | Carboxylesterase 1E; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. | 0.590 |
| Aadac | Ces1g | ENSMUSP00000029325 | ENSMUSP00000037555 | Arylacetamide deacetylase; Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly (By similarity). Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | 0.550 |
| Apob | Aadac | ENSMUSP00000036044 | ENSMUSP00000029325 | Apolipoprotein B-100; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | Arylacetamide deacetylase; Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly (By similarity). Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. | 0.487 |
| Apob | Ces1g | ENSMUSP00000036044 | ENSMUSP00000037555 | Apolipoprotein B-100; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | 0.436 |
| Ces1e | Aadac | ENSMUSP00000034173 | ENSMUSP00000029325 | Carboxylesterase 1E; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. | Arylacetamide deacetylase; Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly (By similarity). Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. | 0.590 |
| Ces1e | Ces1g | ENSMUSP00000034173 | ENSMUSP00000037555 | Carboxylesterase 1E; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | 0.406 |
| Ces1e | Nceh1 | ENSMUSP00000034173 | ENSMUSP00000045864 | Carboxylesterase 1E; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. | Neutral cholesterol ester hydrolase 1; Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. | 0.459 |
| Ces1g | Aadac | ENSMUSP00000037555 | ENSMUSP00000029325 | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | Arylacetamide deacetylase; Displays cellular triglyceride lipase activity in liver, increases the levels of intracellular fatty acids derived from the hydrolysis of newly formed triglyceride stores and plays a role in very low-density lipoprotein assembly (By similarity). Displays serine esterase activity in liver. Deacetylates a variety of arylacetamide substrates, including xenobiotic compounds and procarcinogens, converting them to the primary arylamide compounds and increasing their toxicity. | 0.550 |
| Ces1g | Apob | ENSMUSP00000037555 | ENSMUSP00000036044 | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | Apolipoprotein B-100; Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B- 100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor. | 0.436 |
| Ces1g | Ces1e | ENSMUSP00000037555 | ENSMUSP00000034173 | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | Carboxylesterase 1E; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. | 0.406 |
| Ces1g | Cyp2c29 | ENSMUSP00000037555 | ENSMUSP00000003137 | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | Cytochrome P450 2C29; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET). | 0.577 |
| Ces1g | Cyp2j5 | ENSMUSP00000037555 | ENSMUSP00000030299 | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | Cytochrome P450 2J5. | 0.408 |
| Ces1g | Nceh1 | ENSMUSP00000037555 | ENSMUSP00000045864 | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | Neutral cholesterol ester hydrolase 1; Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. | 0.407 |
| Cyp2c29 | Ces1g | ENSMUSP00000003137 | ENSMUSP00000037555 | Cytochrome P450 2C29; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET). | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | 0.577 |
| Cyp2c29 | Cyp2j5 | ENSMUSP00000003137 | ENSMUSP00000030299 | Cytochrome P450 2C29; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET). | Cytochrome P450 2J5. | 0.812 |
| Cyp2j5 | Ces1g | ENSMUSP00000030299 | ENSMUSP00000037555 | Cytochrome P450 2J5. | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | 0.408 |
| Cyp2j5 | Cyp2c29 | ENSMUSP00000030299 | ENSMUSP00000003137 | Cytochrome P450 2J5. | Cytochrome P450 2C29; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET). | 0.812 |
| Nceh1 | Ces1e | ENSMUSP00000045864 | ENSMUSP00000034173 | Neutral cholesterol ester hydrolase 1; Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. | Carboxylesterase 1E; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. | 0.459 |
| Nceh1 | Ces1g | ENSMUSP00000045864 | ENSMUSP00000037555 | Neutral cholesterol ester hydrolase 1; Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. | Liver carboxylesterase 1; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs; Belongs to the type-B carboxylesterase/lipase family. | 0.407 |