node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bop1 | Krr1 | ENSMUSP00000023217 | ENSMUSP00000125746 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | 0.584 |
Bop1 | Nifk | ENSMUSP00000023217 | ENSMUSP00000027626 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.956 |
Bop1 | Ttc27 | ENSMUSP00000023217 | ENSMUSP00000024882 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Tetratricopeptide repeat protein 27. | 0.541 |
Bop1 | Wdr12 | ENSMUSP00000023217 | ENSMUSP00000027173 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.999 |
Bop1 | Wdr18 | ENSMUSP00000023217 | ENSMUSP00000041049 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | WD repeat-containing protein 18; May play a role during development (By similarity). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes; Belongs to the WD repeat IPI3/WDR18 family. | 0.923 |
Bop1 | Wdr46 | ENSMUSP00000023217 | ENSMUSP00000025170 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | WD repeat-containing protein 46; Scaffold component of the nucleolar structure. Required for localization of DDX21 and NCL to the granular compartment of the nucleolus. | 0.865 |
Bop1 | Wdr55 | ENSMUSP00000023217 | ENSMUSP00000039010 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. | 0.623 |
Bop1 | Wdr74 | ENSMUSP00000023217 | ENSMUSP00000043315 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development. | 0.991 |
Ik | Wdr55 | ENSMUSP00000007042 | ENSMUSP00000039010 | Protein Red; Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species. Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1. | WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. | 0.899 |
Ik | Zmat2 | ENSMUSP00000007042 | ENSMUSP00000001419 | Protein Red; Involved in pre-mRNA splicing as a component of the spliceosome. Auxiliary spliceosomal protein that regulates selection of alternative splice sites in a small set of target pre-mRNA species. Required for normal mitotic cell cycle progression. Recruits MAD1L1 and MAD2L1 to kinetochores, and is required to trigger the spindle assembly checkpoint. Required for normal accumulation of SMU1. | Zinc finger matrin-type protein 2; Involved in pre-mRNA splicing as a component of the spliceosome. | 0.908 |
Krr1 | Bop1 | ENSMUSP00000125746 | ENSMUSP00000023217 | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.584 |
Krr1 | Nifk | ENSMUSP00000125746 | ENSMUSP00000027626 | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | MKI67 FHA domain-interacting nucleolar phosphoprotein. | 0.973 |
Krr1 | Wdr12 | ENSMUSP00000125746 | ENSMUSP00000027173 | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.722 |
Krr1 | Wdr18 | ENSMUSP00000125746 | ENSMUSP00000041049 | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | WD repeat-containing protein 18; May play a role during development (By similarity). Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes; Belongs to the WD repeat IPI3/WDR18 family. | 0.650 |
Krr1 | Wdr46 | ENSMUSP00000125746 | ENSMUSP00000025170 | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | WD repeat-containing protein 46; Scaffold component of the nucleolar structure. Required for localization of DDX21 and NCL to the granular compartment of the nucleolus. | 0.999 |
Krr1 | Wdr55 | ENSMUSP00000125746 | ENSMUSP00000039010 | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. | 0.597 |
Krr1 | Wdr74 | ENSMUSP00000125746 | ENSMUSP00000043315 | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development. | 0.830 |
Nifk | Bop1 | ENSMUSP00000027626 | ENSMUSP00000023217 | MKI67 FHA domain-interacting nucleolar phosphoprotein. | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.956 |
Nifk | Krr1 | ENSMUSP00000027626 | ENSMUSP00000125746 | MKI67 FHA domain-interacting nucleolar phosphoprotein. | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | 0.973 |
Nifk | Wdr12 | ENSMUSP00000027626 | ENSMUSP00000027173 | MKI67 FHA domain-interacting nucleolar phosphoprotein. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.996 |