node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dtna | Hmx3 | ENSMUSP00000111498 | ENSMUSP00000039018 | Dystrobrevin alpha; Involved in synapse maturation and required for normal muscle function. | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | 0.478 |
Dtna | Ppp1r21 | ENSMUSP00000111498 | ENSMUSP00000048443 | Dystrobrevin alpha; Involved in synapse maturation and required for normal muscle function. | Protein phosphatase 1 regulatory subunit 21; utative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. | 0.776 |
Dtnb | Hmx3 | ENSMUSP00000126194 | ENSMUSP00000039018 | Dystrobrevin beta. | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | 0.478 |
Dtnb | Ppp1r21 | ENSMUSP00000126194 | ENSMUSP00000048443 | Dystrobrevin beta. | Protein phosphatase 1 regulatory subunit 21; utative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. | 0.776 |
Gm3194 | Gm3383 | ENSMUSP00000137641 | ENSMUSP00000136657 | Predicted gene 3194. | Predicted gene 3194. | 0.839 |
Gm3194 | Hmx3 | ENSMUSP00000137641 | ENSMUSP00000039018 | Predicted gene 3194. | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | 0.478 |
Gm3383 | Gm3194 | ENSMUSP00000136657 | ENSMUSP00000137641 | Predicted gene 3194. | Predicted gene 3194. | 0.839 |
Gm3383 | Hmx3 | ENSMUSP00000136657 | ENSMUSP00000039018 | Predicted gene 3194. | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | 0.478 |
Hinfp | Hmx3 | ENSMUSP00000149879 | ENSMUSP00000039018 | Histone H4 transcription factor; Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter. | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | 0.559 |
Hmx3 | Dtna | ENSMUSP00000039018 | ENSMUSP00000111498 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | Dystrobrevin alpha; Involved in synapse maturation and required for normal muscle function. | 0.478 |
Hmx3 | Dtnb | ENSMUSP00000039018 | ENSMUSP00000126194 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | Dystrobrevin beta. | 0.478 |
Hmx3 | Gm3194 | ENSMUSP00000039018 | ENSMUSP00000137641 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | Predicted gene 3194. | 0.478 |
Hmx3 | Gm3383 | ENSMUSP00000039018 | ENSMUSP00000136657 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | Predicted gene 3194. | 0.478 |
Hmx3 | Hinfp | ENSMUSP00000039018 | ENSMUSP00000149879 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | Histone H4 transcription factor; Transcriptional repressor that binds to the consensus sequence 5'-CGGACGTT-3' and to the RB1 promoter. Transcriptional activator that promotes histone H4 gene transcription at the G1/S phase transition in conjunction with NPAT. Also activates transcription of the ATM and PRKDC genes. Autoregulates its expression by associating with its own promoter. | 0.559 |
Hmx3 | Lhx6 | ENSMUSP00000039018 | ENSMUSP00000108584 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | LIM/homeobox protein Lhx6; Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. | 0.683 |
Hmx3 | Lhx8 | ENSMUSP00000039018 | ENSMUSP00000136047 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | LIM/homeobox protein Lhx8; Transcription factor involved in differentiation of certain neurons and mesenchymal cells. | 0.479 |
Hmx3 | Pax2 | ENSMUSP00000039018 | ENSMUSP00000134661 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | Paired box protein Pax-2; Transcription factor that may have a role in kidney cell differentiation. | 0.507 |
Hmx3 | Ppp1r21 | ENSMUSP00000039018 | ENSMUSP00000048443 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | Protein phosphatase 1 regulatory subunit 21; utative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway. | 0.559 |
Hmx3 | Tbx1 | ENSMUSP00000039018 | ENSMUSP00000156061 | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | T-box transcription factor TBX1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries. | 0.514 |
Lhx6 | Hmx3 | ENSMUSP00000108584 | ENSMUSP00000039018 | LIM/homeobox protein Lhx6; Probable transcription factor required for the expression of a subset of genes involved in interneurons migration and development. Functions in the specification of cortical interneuron subtypes and in the migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. | Homeobox protein HMX3; Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS; Belongs to the HMX homeobox family. | 0.683 |