Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Dbil5Diazepam-binding inhibitor-like 5; May be involved in the energy metabolism of the mature sperm; Belongs to the ACBP family. (87 aa)    
Predicted Functional Partners:
Dbi
Acyl-CoA-binding protein; Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.
  
 
0.871
Ttc39d
Tetratricopeptide repeat domain 39D.
   
  
 0.648
Fhl4
Four and a half LIM domains 4.
   
  
 0.636
4921536K21Rik
Uncharacterized protein C5orf52 homolog.
   
  
 0.635
Ttc41
Tetratricopeptide repeat protein 41.
   
  
 0.616
Gm12253
Predicted gene 12253.
      
 0.591
Akap4
A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility.
   
  
 0.580
Fsip2
Fibrous sheath-interacting protein 2; Plays a role in spermatogenesis.
   
  
 0.568
Lypd9
LY6/PLAUR domain-containing 9.
   
  
 0.556
Tsn
Translin; DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots. Belongs to the translin family.
    
 
 0.529
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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