| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Asap2 | Ica1 | ENSMUSP00000063217 | ENSMUSP00000040062 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration (By similarity). | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | 0.531 |
| Asap2 | Pkp2 | ENSMUSP00000063217 | ENSMUSP00000036890 | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration (By similarity). | Plakophilin 2. | 0.438 |
| Glcci1 | Ica1 | ENSMUSP00000069444 | ENSMUSP00000040062 | Glucocorticoid-induced transcript 1 protein. | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | 0.512 |
| Gm49486 | Ica1 | ENSMUSP00000061125 | ENSMUSP00000040062 | Galectin. | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | 0.514 |
| Ica1 | Asap2 | ENSMUSP00000040062 | ENSMUSP00000063217 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration (By similarity). | 0.531 |
| Ica1 | Glcci1 | ENSMUSP00000040062 | ENSMUSP00000069444 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | Glucocorticoid-induced transcript 1 protein. | 0.512 |
| Ica1 | Gm49486 | ENSMUSP00000040062 | ENSMUSP00000061125 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | Galectin. | 0.514 |
| Ica1 | Pick1 | ENSMUSP00000040062 | ENSMUSP00000128126 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | PRKCA-binding protein; Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive w [...] | 0.886 |
| Ica1 | Pkp2 | ENSMUSP00000040062 | ENSMUSP00000036890 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | Plakophilin 2. | 0.491 |
| Ica1 | Ptprn2 | ENSMUSP00000040062 | ENSMUSP00000064046 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | Receptor-type tyrosine-protein phosphatase N2; Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain. In females, but not in males, required for normal accumulation and secretion of pituitary hormones [...] | 0.478 |
| Ica1 | Rab2a | ENSMUSP00000040062 | ENSMUSP00000057664 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | Ras-related protein Rab-2A; Required for protein transport from the endoplasmic reticulum to the Golgi complex. | 0.759 |
| Ica1 | Ralgapa2 | ENSMUSP00000040062 | ENSMUSP00000105613 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | Ral GTPase-activating protein subunit alpha-2; Catalytic subunit of the heterodimeric RalGAP2 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB. | 0.553 |
| Ica1 | Shisa9 | ENSMUSP00000040062 | ENSMUSP00000132646 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | Protein shisa-9; Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses; Belongs to the shisa family. SHISA9 subfamily. | 0.511 |
| Ica1 | Slc30a8 | ENSMUSP00000040062 | ENSMUSP00000035257 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | Zinc transporter 8; Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells (By similarity). | 0.513 |
| Pick1 | Ica1 | ENSMUSP00000128126 | ENSMUSP00000040062 | PRKCA-binding protein; Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive w [...] | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | 0.886 |
| Pick1 | Rab2a | ENSMUSP00000128126 | ENSMUSP00000057664 | PRKCA-binding protein; Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive w [...] | Ras-related protein Rab-2A; Required for protein transport from the endoplasmic reticulum to the Golgi complex. | 0.404 |
| Pkp2 | Asap2 | ENSMUSP00000036890 | ENSMUSP00000063217 | Plakophilin 2. | Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2; Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration (By similarity). | 0.438 |
| Pkp2 | Ica1 | ENSMUSP00000036890 | ENSMUSP00000040062 | Plakophilin 2. | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | 0.491 |
| Ptprn2 | Ica1 | ENSMUSP00000064046 | ENSMUSP00000040062 | Receptor-type tyrosine-protein phosphatase N2; Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain. In females, but not in males, required for normal accumulation and secretion of pituitary hormones [...] | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | 0.478 |
| Ptprn2 | Slc30a8 | ENSMUSP00000064046 | ENSMUSP00000035257 | Receptor-type tyrosine-protein phosphatase N2; Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets. Required for the accumulation of normal levels of insulin-containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain. In females, but not in males, required for normal accumulation and secretion of pituitary hormones [...] | Zinc transporter 8; Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta-cells (By similarity). | 0.621 |
