node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atoh8 | Col6a2 | ENSMUSP00000036981 | ENSMUSP00000001181 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity). Regulates endothelial cell proliferation, migration and tube-like structures formation (By similarity). Modulates endothelial cell differentiation through NOS3 (By similarity). May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. During early [...] | Collagen alpha-2(VI) chain; Collagen VI acts as a cell-binding protein. | 0.414 |
Atoh8 | Copz2 | ENSMUSP00000036981 | ENSMUSP00000018816 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity). Regulates endothelial cell proliferation, migration and tube-like structures formation (By similarity). Modulates endothelial cell differentiation through NOS3 (By similarity). May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. During early [...] | Coatomer subunit zeta-2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properti [...] | 0.560 |
Atoh8 | Efemp2 | ENSMUSP00000036981 | ENSMUSP00000064719 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity). Regulates endothelial cell proliferation, migration and tube-like structures formation (By similarity). Modulates endothelial cell differentiation through NOS3 (By similarity). May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. During early [...] | EGF-containing fibulin-like extracellular matrix protein 2; Belongs to the fibulin family. | 0.543 |
Atoh8 | Fkbp10 | ENSMUSP00000036981 | ENSMUSP00000001595 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity). Regulates endothelial cell proliferation, migration and tube-like structures formation (By similarity). Modulates endothelial cell differentiation through NOS3 (By similarity). May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. During early [...] | Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis. | 0.523 |
Atoh8 | Mrgprf | ENSMUSP00000036981 | ENSMUSP00000033386 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity). Regulates endothelial cell proliferation, migration and tube-like structures formation (By similarity). Modulates endothelial cell differentiation through NOS3 (By similarity). May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. During early [...] | Mas-related G-protein coupled receptor member F; Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain; Belongs to the G-protein coupled receptor 1 family. Mas subfamily. | 0.571 |
Atoh8 | Prrx2 | ENSMUSP00000036981 | ENSMUSP00000040332 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity). Regulates endothelial cell proliferation, migration and tube-like structures formation (By similarity). Modulates endothelial cell differentiation through NOS3 (By similarity). May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. During early [...] | Paired mesoderm homeobox protein 2; Belongs to the paired homeobox family. | 0.558 |
Atoh8 | Tgfb1i1 | ENSMUSP00000036981 | ENSMUSP00000132100 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity). Regulates endothelial cell proliferation, migration and tube-like structures formation (By similarity). Modulates endothelial cell differentiation through NOS3 (By similarity). May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. During early [...] | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. [...] | 0.501 |
Atoh8 | Vgll3 | ENSMUSP00000036981 | ENSMUSP00000131500 | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity). Regulates endothelial cell proliferation, migration and tube-like structures formation (By similarity). Modulates endothelial cell differentiation through NOS3 (By similarity). May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. During early [...] | Transcription cofactor vestigial-like protein 3; May act as a specific coactivator for the mammalian TEFs. Belongs to the vestigial family. | 0.575 |
Bgn | Col6a2 | ENSMUSP00000033741 | ENSMUSP00000001181 | Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Collagen alpha-2(VI) chain; Collagen VI acts as a cell-binding protein. | 0.852 |
Bgn | Copz2 | ENSMUSP00000033741 | ENSMUSP00000018816 | Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Coatomer subunit zeta-2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properti [...] | 0.518 |
Bgn | Efemp2 | ENSMUSP00000033741 | ENSMUSP00000064719 | Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | EGF-containing fibulin-like extracellular matrix protein 2; Belongs to the fibulin family. | 0.602 |
Bgn | Fkbp10 | ENSMUSP00000033741 | ENSMUSP00000001595 | Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Peptidyl-prolyl cis-trans isomerase FKBP10; PPIases accelerate the folding of proteins during protein synthesis. | 0.593 |
Bgn | Mrgprf | ENSMUSP00000033741 | ENSMUSP00000033386 | Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Mas-related G-protein coupled receptor member F; Orphan receptor. May bind to a neuropeptide and may regulate nociceptor function and/or development, including the sensation or modulation of pain; Belongs to the G-protein coupled receptor 1 family. Mas subfamily. | 0.432 |
Bgn | Prrx2 | ENSMUSP00000033741 | ENSMUSP00000040332 | Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Paired mesoderm homeobox protein 2; Belongs to the paired homeobox family. | 0.531 |
Bgn | Tgfb1i1 | ENSMUSP00000033741 | ENSMUSP00000132100 | Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. [...] | 0.431 |
Bgn | Vgll3 | ENSMUSP00000033741 | ENSMUSP00000131500 | Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Transcription cofactor vestigial-like protein 3; May act as a specific coactivator for the mammalian TEFs. Belongs to the vestigial family. | 0.415 |
Col6a2 | Atoh8 | ENSMUSP00000001181 | ENSMUSP00000036981 | Collagen alpha-2(VI) chain; Collagen VI acts as a cell-binding protein. | Protein atonal homolog 8; Transcription factor that binds a palindromic (canonical) core consensus DNA sequence 5'-CANNTG- 3' known as an E-box element, possibly as a heterodimer with other bHLH proteins (By similarity). Regulates endothelial cell proliferation, migration and tube-like structures formation (By similarity). Modulates endothelial cell differentiation through NOS3 (By similarity). May be implicated in specification and differentiation of neuronal cell lineages in the brain. May participate in kidney development and may be involved in podocyte differentiation. During early [...] | 0.414 |
Col6a2 | Bgn | ENSMUSP00000001181 | ENSMUSP00000033741 | Collagen alpha-2(VI) chain; Collagen VI acts as a cell-binding protein. | Biglycan; May be involved in collagen fiber assembly; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | 0.852 |
Col6a2 | Copz2 | ENSMUSP00000001181 | ENSMUSP00000018816 | Collagen alpha-2(VI) chain; Collagen VI acts as a cell-binding protein. | Coatomer subunit zeta-2; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properti [...] | 0.572 |
Col6a2 | Efemp2 | ENSMUSP00000001181 | ENSMUSP00000064719 | Collagen alpha-2(VI) chain; Collagen VI acts as a cell-binding protein. | EGF-containing fibulin-like extracellular matrix protein 2; Belongs to the fibulin family. | 0.591 |