node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adprhl1 | Grtp1 | ENSMUSP00000033825 | ENSMUSP00000148042 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; Seems not to catalyse the hydrolysis of O-acetyl-ADP-ribose. | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | 0.730 |
Adprhl1 | Pcid2 | ENSMUSP00000033825 | ENSMUSP00000133204 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; Seems not to catalyse the hydrolysis of O-acetyl-ADP-ribose. | PCI domain-containing protein 2; Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells (By similarity). | 0.408 |
Adprhl1 | Tmco3 | ENSMUSP00000033825 | ENSMUSP00000040347 | [Protein ADP-ribosylarginine] hydrolase-like protein 1; Seems not to catalyse the hydrolysis of O-acetyl-ADP-ribose. | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter. | 0.550 |
Gm28042 | Nqo1 | ENSMUSP00000115498 | ENSMUSP00000003947 | Phospholipase A2. | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. | 0.572 |
Gm28042 | Nqo2 | ENSMUSP00000115498 | ENSMUSP00000053809 | Phospholipase A2. | Ribosyldihydronicotinamide dehydrogenase [quinone]; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. | 0.572 |
Gm28042 | Tmco3 | ENSMUSP00000115498 | ENSMUSP00000040347 | Phospholipase A2. | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter. | 0.606 |
Gm28042 | Treh | ENSMUSP00000115498 | ENSMUSP00000034609 | Phospholipase A2. | Trehalase; Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose; Belongs to the glycosyl hydrolase 37 family. | 0.521 |
Gm28042 | Yipf6 | ENSMUSP00000115498 | ENSMUSP00000056039 | Phospholipase A2. | Protein YIPF6; May be required for stable YIPF1 and YIPF2 protein expression. | 0.520 |
Grtp1 | Adprhl1 | ENSMUSP00000148042 | ENSMUSP00000033825 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | [Protein ADP-ribosylarginine] hydrolase-like protein 1; Seems not to catalyse the hydrolysis of O-acetyl-ADP-ribose. | 0.730 |
Grtp1 | Pcid2 | ENSMUSP00000148042 | ENSMUSP00000133204 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | PCI domain-containing protein 2; Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells (By similarity). | 0.625 |
Grtp1 | Tfdp1 | ENSMUSP00000148042 | ENSMUSP00000147881 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | Transcription factor Dp-1; Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters. | 0.447 |
Grtp1 | Tmco3 | ENSMUSP00000148042 | ENSMUSP00000040347 | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter. | 0.639 |
Mri1 | Tmco3 | ENSMUSP00000122623 | ENSMUSP00000040347 | Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter. | 0.561 |
Nqo1 | Gm28042 | ENSMUSP00000003947 | ENSMUSP00000115498 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. | Phospholipase A2. | 0.572 |
Nqo1 | Tmco3 | ENSMUSP00000003947 | ENSMUSP00000040347 | NAD(P)H dehydrogenase [quinone] 1; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter. | 0.599 |
Nqo2 | Gm28042 | ENSMUSP00000053809 | ENSMUSP00000115498 | Ribosyldihydronicotinamide dehydrogenase [quinone]; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. | Phospholipase A2. | 0.572 |
Nqo2 | Tmco3 | ENSMUSP00000053809 | ENSMUSP00000040347 | Ribosyldihydronicotinamide dehydrogenase [quinone]; The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter. | 0.599 |
Pcid2 | Adprhl1 | ENSMUSP00000133204 | ENSMUSP00000033825 | PCI domain-containing protein 2; Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells (By similarity). | [Protein ADP-ribosylarginine] hydrolase-like protein 1; Seems not to catalyse the hydrolysis of O-acetyl-ADP-ribose. | 0.408 |
Pcid2 | Grtp1 | ENSMUSP00000133204 | ENSMUSP00000148042 | PCI domain-containing protein 2; Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells (By similarity). | Growth hormone-regulated TBC protein 1; May act as a GTPase-activating protein for Rab family protein(s). | 0.625 |
Pcid2 | Tmco3 | ENSMUSP00000133204 | ENSMUSP00000040347 | PCI domain-containing protein 2; Required for B-cell survival through the regulation of the expression of cell-cycle checkpoint MAD2L1 protein during B cell differentiation. As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores (By similarity). Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and transcription-associated genomic instability. R-loop accumulation does not increase in PCID2-depleted cells (By similarity). | Transmembrane and coiled-coil domain-containing protein 3; Probable Na(+)/H(+) antiporter. | 0.595 |