node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adgrl1 | Lrrc18 | ENSMUSP00000118452 | ENSMUSP00000041199 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.526 |
Adgrl2 | Lrrc18 | ENSMUSP00000143626 | ENSMUSP00000041199 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.526 |
Adgrl3 | Lrrc18 | ENSMUSP00000072336 | ENSMUSP00000041199 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.526 |
Atp6ap1l | Fam47e | ENSMUSP00000105168 | ENSMUSP00000118033 | ATPase, H+-transporting, lysosomal accessory protein 1-like. | Family with sequence similarity 47, member E. | 0.607 |
Atp6ap1l | Lrrc18 | ENSMUSP00000105168 | ENSMUSP00000041199 | ATPase, H+-transporting, lysosomal accessory protein 1-like. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.604 |
Atp6ap1l | Lrrc74b | ENSMUSP00000105168 | ENSMUSP00000097699 | ATPase, H+-transporting, lysosomal accessory protein 1-like. | Leucine-rich repeat-containing protein 74B. | 0.666 |
Drg2 | Lrrc18 | ENSMUSP00000018568 | ENSMUSP00000041199 | Developmentally-regulated GTP-binding protein 2; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.610 |
Fam170b | Lrrc18 | ENSMUSP00000100529 | ENSMUSP00000041199 | Protein FAM170B; Plays a role in fertilization through the acrosome reaction. Belongs to the FAM170 family. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.635 |
Fam170b | Wdfy4 | ENSMUSP00000100529 | ENSMUSP00000057556 | Protein FAM170B; Plays a role in fertilization through the acrosome reaction. Belongs to the FAM170 family. | WD repeat- and FYVE domain-containing protein 4; Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy. | 0.424 |
Fam47e | Atp6ap1l | ENSMUSP00000118033 | ENSMUSP00000105168 | Family with sequence similarity 47, member E. | ATPase, H+-transporting, lysosomal accessory protein 1-like. | 0.607 |
Fam47e | Lrrc18 | ENSMUSP00000118033 | ENSMUSP00000041199 | Family with sequence similarity 47, member E. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.646 |
Fam47e | Lrrc74b | ENSMUSP00000118033 | ENSMUSP00000097699 | Family with sequence similarity 47, member E. | Leucine-rich repeat-containing protein 74B. | 0.716 |
Gm8369 | Lrrc18 | ENSMUSP00000132521 | ENSMUSP00000041199 | Predicted gene 8369. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.667 |
Gm8369 | Wdfy4 | ENSMUSP00000132521 | ENSMUSP00000057556 | Predicted gene 8369. | WD repeat- and FYVE domain-containing protein 4; Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy. | 0.522 |
Lrrc18 | Adgrl1 | ENSMUSP00000041199 | ENSMUSP00000118452 | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.526 |
Lrrc18 | Adgrl2 | ENSMUSP00000041199 | ENSMUSP00000143626 | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | 0.526 |
Lrrc18 | Adgrl3 | ENSMUSP00000041199 | ENSMUSP00000072336 | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | 0.526 |
Lrrc18 | Atp6ap1l | ENSMUSP00000041199 | ENSMUSP00000105168 | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | ATPase, H+-transporting, lysosomal accessory protein 1-like. | 0.604 |
Lrrc18 | Drg2 | ENSMUSP00000041199 | ENSMUSP00000018568 | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | Developmentally-regulated GTP-binding protein 2; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.610 |
Lrrc18 | Fam170b | ENSMUSP00000041199 | ENSMUSP00000100529 | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | Protein FAM170B; Plays a role in fertilization through the acrosome reaction. Belongs to the FAM170 family. | 0.635 |